F8 / FVIII / Factor VIII Antibody
Catalog Number: LS-C23371
2 sizes / from $443.00
Antibody: Sheep Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human
Format: Liquid
Anti-F8 / Factor VIII antibody IHC of human skeletal muscle and capillaries. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IHC-plus™ F8 / FVIII / Factor VIII Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Sheep Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$449.00each
Catalog Number: LS-B2979-0.5
Catalog Number: LS-B2979
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- Description
- Factor VIII antibody LS-B2979 is an unconjugated sheep polyclonal antibody to human Factor VIII (F8 / FVIII). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
- Application
- ELISA, IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AHF | Antihemophilic factor | Coagulation factor VIIIc | Coagulation factor VIII | DXS1253E | Factor VIII F8B | FVIII | HEMA | F8 | F8B | Factor VIII | Procoagulant component | F8C
- Recommended Dilution: IHC-P
- 5 µg/ml
- UniProt Number
- P00451
- NCBI GenBank
- NM_000132 | NP_000123.1
- SwissProt
- P00451
Target
- Target
- F8 / FVIII / Factor VIII
- Antigen Species
- Human
- Specificity
- Recognizes human F. VIII as demonstrated by immunodiffusion and ELISA. No reactivity was observed with von Willebrand Factor.
- Epitope
- Recognizes human F. VIII as demonstrated by immunodiffusion and ELISA. No reactivity was observed with von Willebrand Factor.
- Gene Name
- F8
Antibody
- Host Species
- Sheep
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Human Factor VIIIC (F. VIII) purified from F. VIII concentrate.
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM HEPES, pH 7.4, 0.15 M NaCl, 50% Glycerol
- Concentration
- 10 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Purification Method
- Caprylic Acid / Ammonium Sulfate Precipitation
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- 10 mM HEPES, 0.15 M NaCl
IL-15 blockade and rapamycin rescue multifactorial loss of factor VIII from AAV-transduced hepatocytes in hemophilia A mice. John S S Butterfield, Kentaro Yamada, Thais B Bertolini, Farooq Syed, Sandeep R P Kumar, Xin Li, Sreevani Arisa, Annie R Piñeros, Alejandro Tapia, Christopher A Rogers, Ning Li, Jyoti Rana, Moanaro Biswas, Cox Terhorst, Randal J Kaufman, Ype P de Jong, Roland W Herzog. Molecular therapy : the journal of the American Society of Gene Therapy. 2022 December;30:3552-3569. PubMed: 35821634 PMC: PMC9734025
