LSBio
IHC-plus™ CD46 Antibody (clone MEM-258)

Anti-CD46 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ CD46 Antibody (clone MEM-258)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
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$383.00each
Catalog Number: LS-B5950-0.05

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Overview

Description
CD46 antibody LS-B5950 is an unconjugated mouse monoclonal antibody to human CD46. Validated for Flow, IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Application
FC, IF, IHC, IHC-P, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
AHUS2 | CD46 antigen | CD46 | MCP | Measles virus receptor | TLX | MIC10 | TRA2.10 | Membrane cofactor protein
Recommended Dilution: FC
1:10 - 1:50
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
P15529
SwissProt
P15529

Target

Target
CD46
Antigen Species
Human
Specificity
Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization
Epitope
Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.
Gene Name
CD46

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
MEM-258
Origin Species
Human

Immunogen

Immunogen
HPB-ALL cell line.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.