LSBio
CD46 Antibody (clone MEM-258, Concentrated)

CD46 Antibody (clone MEM-258, Concentrated)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human CD46 antibodies →
$481.00each
Catalog Number: LS-C204148-0.1

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Overview

Description
CD46 antibody LS-C204148 is an unconjugated mouse monoclonal antibody to human CD46. Validated for Flow, IP and WB.
Application
FC, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
AHUS2 | CD46 antigen | CD46 | MCP | Measles virus receptor | TLX | MIC10 | TRA2.10 | Membrane cofactor protein
UniProt Number
P15529
SwissProt
P15529

Target

Target
Human CD46
Antigen Species
Human
Epitope
CD46 antigen (human). The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome.
Gene Name
CD46

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
MEM-258
Isotype
IgG1

Immunogen

Immunogen
HPB-ALL cells.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 15 mM Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Other

Storage & Handling

Storage Conditions
Store at 2-8°C.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.