CAPN2 / Calpain 2 / M-Calpain Antibody
Catalog Number: LS-C667728
4 sizes / from $272.00
Antibody: Rabbit Polyclonal
Applications: Western Blot
Reactivity: Human
Format: Liquid
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
IHC-plus™ CAPN2 / Calpain 2 / M-Calpain Antibody (clone 1F4)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Non-Human Primate, Rat |
| Format: | Liquid |
$470.00each
Catalog Number: LS-B12657-50
Catalog Number: LS-B12657
For bulk orders or custom formulations:
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- Description
- M-Calpain antibody LS-B12657 is an unconjugated mouse monoclonal antibody to M-Calpain (CAPN2 / Calpain 2) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- FC, IHC, IHC-P, WB
- Reactivity
- Hu, Ms, NHP, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Calpain 2, large subunit | Calpain ii | Calpain, large polypeptide L2 | Calpain-2 catalytic subunit | Calpain 2 | Calpain large polypeptide L2 | Calpain-2 large subunit | CANP 2 | CAPN2 | Calpain M-type | CANP2 | CANPL2 | CANPml | M-type calpain | M-calpain | MCANP | Millimolar-calpain
- Recommended Dilution: FC
- 1:100
- Recommended Dilution: IHC-P
- 10 µg/ml
- Recommended Dilution: WB
- 1:500 - 1:2000
- UniProt Number
- P17655
- NCBI GenBank
- NM_001748 | NP_001739.2
- SwissProt
- P17655
Target
- Target
- CAPN2 / Calpain 2 / M-Calpain
- Antigen Species
- Human
- Specificity
- Human CAPN2 / Calpain 2 / M-Calpain
- Epitope
- Human CAPN2 / Calpain 2 / M-Calpain
- Gene Name
- CAPN2
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 1F4
- Origin Species
- Human
Immunogen
- Immunogen
- Full length human recombinant protein of human CAPN2(NP_001739) produced in HEK293T cell.
- Immunogen Type
- Full-Length Recombinant Protein
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
- Concentration
- 0.75 mg/mL
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- No
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation. Wang Y, Hall RA, Lee M, Kamgar-Parsi A, Bi X, Baudry M. Scientific reports. 2017;7:11771.
PubMed: 28924170 · PMC: PMC5603515
Defects in the CAPN1 Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans. Wang Y, Hersheson J, Lopez D, Hammer M, Liu Y, Lee KH, Pinto V, Seinfeld J, Wiethoff S, Sun J, Amouri R, Hentati F, Baudry N, Tran J, Singleton AB, Coutelier M, Brice A, Stevanin G, Durr A, Bi X, Houlden H, Baudry M. Cell reports. 2016;16:79-91.
PubMed: 27320912
