LSBio
IHC-plus™ APOB / Apolipoprotein B Antibody

Anti-Apolipoprotein B antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

IHC-plus™ APOB / Apolipoprotein B Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Other, Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all APOB / Apolipoprotein B antibodies →
$536.00each
Catalog Number: LS-B6180-0.05

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Overview

Description
Apolipoprotein B antibody LS-B6180 is an unconjugated rabbit polyclonal antibody to Apolipoprotein B (APOB) from mouse. It is reactive with human and mouse. Validated for ID, IHC and WB. Cited in 4 publications.
Application
IHC, IHC-P, Other, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ApoB-100 | APOB | Apolipoprotein B-48 | ApoB-48 | Apolipoprotein B | FLDB | LDLCQ4 | Mutant Apo B 100 | Apo B-100 | Apolipoprotein B-100 | Apolipoprotein B48
Recommended Dilution: IHC-P
1:100
UniProt Number
P04114
SwissProt
P04114

Target

Target
APOB / Apolipoprotein B
Antigen Species
Mouse
Specificity
Recognizes human, mouse Apo B48 (241kD) and B100 (513 kD)
Epitope
Recognizes mouse Apo B48 (241kD) and B100 (513kD) as these proteins are highly conserved. Species cross-reactivity: human.
Gene Name
APOB

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Mouse very low density lipoprotein.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
0.02% Sodium Azide
Volume
0.05 Milliliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

Estrogen signaling prevents diet-induced hepatic insulin resistance in male mice with obesity. Zhu L, Martinez MN, Emfinger CH, Palmisano BT, Stafford JM. American journal of physiology. Endocrinology and metabolism. 2014 May;306:E1188-97.

PubMed: 24691030 · PMC: PMC4116406


Estrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistance. Zhu L, Brown WC, Cai Q, Krust A, Chambon P, McGuinness OP, Stafford JM. Diabetes. 2013 Feb;62:424-34.

PubMed: 22966069 · PMC: PMC3554377


Apolipoprotein B48, the Structural Component of Chylomicrons, Is Sufficient to Antagonize Staphylococcus aureus Quorum-Sensing. Elmore BO, Triplett KD, Hall PR. PloS one. 2015;10:e0125027.

PubMed: 25942561 · PMC: PMC4420250


Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding. Zhu L, Shi J, Luu TN, Neuman JC, Trefts E, Yu S, Palmisano BT, Wasserman DH, Linton MF, Stafford JM. Molecular metabolism. 2018 February;8:106-116.

PubMed: 29331506 · PMC: PMC5985047

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