LSBio
IHC-plus™ ABCB1 / MDR1 / P Glycoprotein Antibody (Cytoplasmic Domain)

Anti-ABCB1 / MDR1 antibody IHC of human adrenal, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ ABCB1 / MDR1 / P Glycoprotein Antibody (Cytoplasmic Domain)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all ABCB1 / MDR1 / P Glycoprotein antibodies →
$403.00each
Catalog Number: LS-A9403-50

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Overview

Description
P Glycoprotein antibody LS-A9403 is an unconjugated rabbit polyclonal antibody to human P Glycoprotein (ABCB1 / MDR1) (Cytoplasmic Domain). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC
Reactivity
Hu
Predicted Reactivity
Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ABC20 | ABCB1 | Abcb1b | CLCS | Colchicin sensitivity | CD243 | IBD13 | gp170 | MDR1 | Multidrug resistance protein 1 | P glycoprotein | P-glycoprotein 1 | P-GP | CD243 antigen | PGY1 | Abcb1
Recommended Dilution: IHC-P
2.5 - 5 µg/ml
UniProt Number
P08183
SwissProt
P08183

Target

Target
ABCB1 / MDR1 / P Glycoprotein
Antigen Species
Human
Specificity
Human ABCB1 / MDR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human ABCB1 / MDR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
ABCB1

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 17 amino acid peptide from cytoplasmic domain of human ABCB1 / MDR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (94%); Mouse, Hamster (82%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia. Kleberg K, Jensen GM, Christensen DP, Lundh M, Grunnet LG, Knuhtsen S, Poulsen SS, Hansen MB, Bindslev N. BMC gastroenterology. 2012;12:78. PubMed: 22734885 PMC: PMC3457850

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