Anti-MDR1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

IHC-plus™ ABCB1 / MDR1 / P Glycoprotein Antibody (clone JSB-1)

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Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot
Reactivity:	Human
Format:	Liquid

See all ABCB1 / MDR1 / P Glycoprotein antibodies â†’

$470.00each

Catalog Number: LS-B5570-100

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Overview

Description: P Glycoprotein antibody LS-B5570 is an unconjugated mouse monoclonal antibody to human P Glycoprotein (ABCB1 / MDR1). Validated for Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Application: FC, IHC, IHC-F, IHC-P, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: ABC20 | ABCB1 | Abcb1b | CLCS | Colchicin sensitivity | CD243 | IBD13 | gp170 | MDR1 | Multidrug resistance protein 1 | P glycoprotein | P-glycoprotein 1 | P-GP | CD243 antigen | PGY1
Recommended Dilution: IHC-P: 1:50
UniProt Number: P08183
NCBI GenBank: NM_000927 | NP_000918.2
SwissProt: P08183

Target

Target: ABCB1 / MDR1 / P Glycoprotein
Antigen Species: Human
Specificity: The antibody JSB-1 reacts with a conserved cytoplasmic epitope of the plasma membrane-associated 170-180 kD glycoprotein, the expression of which is strongly correlated with the degree of multi-drug-resistance (MDR) derived MDR cell lines and human MDR cell lines, including cell lines derived from lung, ovaries and B cell lymphomas. Cross-reacts with Chinese hamster. No cross-reactivity with mouse or rat.
Epitope: The antibody JSB-1 reacts with a conserved cytoplasmic epitope of the plasma membrane-associated 170-180 kD glycoprotein, the expression of which is strongly correlated with the degree of multi-drug-resistance (MDR) derived MDR cell lines and human MDR cell lines, including cell lines derived from lung, ovaries and B cell lymphomas. Cross-reacts with Chinese hamster. No cross-reactivity with mouse or rat.
Gene Name: ABCB1