Formalin-fixed, paraffin-embedded human Tonsil stained with IgM Mouse Recombinant Monoclonal Antibody (rIM373).
IGHM / IgM Antibody (clone rIM373)
Secondary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751200-20
Catalog Number: LS-C751200
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- Description
- IgM antibody LS-C751200 is an unconjugated mouse recombinant monoclonal antibody to human IgM (IGHM). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Secondary Antibodies
- Alternative Names
- AGM1 | IGM | MU | VH | IGHM
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P01871
- SwissProt
- P01871
Target
- Target
- Human IGHM / IgM
- Antigen Species
- Human
- Epitope
- Recognizes a protein of 75 kDa , identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rIM373
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
Immunogen
- Immunogen
- Heavy chain of human IgM. Antigen Molecular Weight: 50-75 kDa
- Immunogen Type
- Native Protein (Purified from Natural Source)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS