LSBio
Histone H3 Antibody (Citrulline-Arg2/8/17, clone 7C10)

Histone H3 Antibody (Citrulline-Arg2/8/17, clone 7C10)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Reactivity:Human
Format:Lyophilized
See all Human Histone H3 antibodies →
$449.00each
Catalog Number: LS-C144555-50

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Overview

Description
Histone H3 antibody LS-C144555 is an unconjugated mouse monoclonal antibody to human Histone H3 (Citrulline-Arg2/8/17). Validated for ELISA, Flow, ICC and IF. Cited in 2 publications.
Application
ELISA, FC, ICC, IF
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: IF/ICC
1:100 - 1:500

Target

Target
Human Histone H3
Antigen Species
Human
Epitope
Monoclonal antibody reacts specifically with human Histone H3 Citrulline at the 3 positions: 2, 8 and 17 The antibody doesn't react with mono or bis H3-Cit

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
7C10
Isotype
IgG1
Light Chain
Kappa Light Chain

Immunogen

Immunogen
Synthetic peptide derived from Nter domain of human Histone H3 containing Citrulline at position 2-8-17.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from PBS, 0.02% Sodium Azide
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store lyophilized at -20°C for 2 years. Stable at 4°C for up to 1 month or for 6 months in aliquots at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes. Vecchio F, Lo Buono N, Stabilini A, Nigi L, Dufort MJ, Geyer S, Rancoita PM, Cugnata F, Mandelli A, Valle A, Leete P, Mancarella F, Linsley PS, Krogvold L, Herold KC, Elding Larsson H, Richardson SJ, Morgan NG, Dahl-Jørgensen K, Sebastiani G, Dotta F, Bosi E; DRI_Biorepository Group; Type 1 Diabetes TrialNet Study Group, Battaglia M. JCI insight. 2018 September;3:pii: 122146.

PubMed: 30232284 · PMC: PMC6237216


Increased Mortality in Mice following Immunoprophylaxis Therapy with High Dosage of Nicotinamide in Burkholderia Persistent Infections. Micheva-Viteva SN, Ross BN, Gao J, Adikari S, Zhang P, Mourant JR, Wu TH, Werner JH, Torres AG, Hong-Geller E. Infection and immunity. 2018 December;87:pii e00592-18.

PubMed: 30323029 · PMC: PMC6300628

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