FZD9 / Frizzled 9 Antibody (FITC)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C498896-50

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Description: Frizzled 9 antibody LS-C498896 is an FITC-conjugated rabbit polyclonal antibody to human Frizzled 9 (FZD9). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: CD349 | Frizzled homolog 9 | Fz-9 | Frizzled family receptor 9 | Frizzled-9 | Frizzled 9 | Fz9 | HFz9 | CD349 antigen | Frizzled homolog fzd3 | FZD9 | FzE6
UniProt Number: O00144
NCBI GenBank: NM_003508 | NP_003499.1
SwissProt: O00144

Target: Human FZD9 / Frizzled 9
Antigen Species: Human
Epitope: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Gene Name: FZD9

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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