Positive WB detected in:Mouse liver tissue,Mouse kidney tissue;All lanes: FZD9 antibody at 2.5ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 65 kDa;Observed band size: 65 kDa;
FZD9 / Frizzled 9 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C498881-50
Catalog Number: LS-C498881
For bulk orders or custom formulations:
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- Description
- Frizzled 9 antibody LS-C498881 is an unconjugated rabbit polyclonal antibody to Frizzled 9 (FZD9) from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB.
- Application
- ELISA, IHC, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CD349 | Frizzled homolog 9 | Fz-9 | Frizzled family receptor 9 | Frizzled-9 | Frizzled 9 | Fz9 | HFz9 | CD349 antigen | Frizzled homolog fzd3 | FZD9 | FzE6
- UniProt Number
- O00144
- NCBI GenBank
- NM_003508 | NP_003499.1
- SwissProt
- O00144
Target
- Target
- Human FZD9 / Frizzled 9
- Antigen Species
- Human
- Epitope
- Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
- Gene Name
- FZD9
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Frizzled-9 protein (23-229AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS