LSBio
DXO / DOM3Z Antibody

Immunohistochemistry of paraffin-embedded human testis tissue using DXO Antibody at dilution of 1:100

DXO / DOM3Z Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human DXO / DOM3Z antibodies →
$300.00each
Catalog Number: LS-C498725-50

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Overview

Description
DOM3Z antibody LS-C498725 is an unconjugated rabbit polyclonal antibody to human DOM3Z (DXO). Validated for ELISA, IF and IHC.
Application
ELISA, IF, IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Dom-3 homolog Z | DOM3L | Dom-3 homolog Z (C. elegans) | DOM3Z | DOM-3 (C. elegans) homolog Z | NG6 | Protein Dom3Z | decapping and exoribonuclease protein
UniProt Number
O77932
SwissProt
O77932

Target

Target
Human DXO / DOM3Z
Antigen Species
Human
Epitope
Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity).
Gene Name
DXO

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Decapping and exoribonuclease protein protein (69-266AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.