DXO / DOM3Z Antibody (Biotin)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C498743-50

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Description: DOM3Z antibody LS-C498743 is a biotin-conjugated rabbit polyclonal antibody to human DOM3Z (DXO). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Dom-3 homolog Z | DOM3L | Dom-3 homolog Z (C. elegans) | DOM3Z | DOM-3 (C. elegans) homolog Z | NG6 | Protein Dom3Z | decapping and exoribonuclease protein
UniProt Number: O77932
NCBI GenBank: NM_005510 | NP_005501.2
SwissProt: O77932

Target: Human DXO / DOM3Z
Antigen Species: Human
Epitope: Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity).
Gene Name: DXO

Immunogen: Recombinant Human Decapping and exoribonuclease protein protein (69-266AA)
Immunogen Type: Recombinant Immunogen

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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