Positive WB detected in:HEK293 whole cell lysate,Mouse liver tissue;All lanes:DLL4 antibody at 4ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 75 kDa;Observed band size: 75 kDa;

DLL4 Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity:	Human, Mouse
Format:	Liquid

$300.00each

Catalog Number: LS-C498707-50

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Overview

Description: DLL4 antibody LS-C498707 is an unconjugated rabbit polyclonal antibody to DLL4 from human. It is reactive with human and mouse. Validated for ELISA and WB.
Application: ELISA, IHC, WB
Reactivity: Hu, Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Delta-like 4 protein | Delta like 4 | Delta-like 4 (Drosophila) | Delta-like 4 homolog | DLL4 | Drosophila Delta homolog 4 | Notch ligand DLL4 | Delta 4 | Delta ligand 4 | Delta-like protein 4 | Delta4 | Hdelta2 | Notch ligand delta-2
UniProt Number: Q9NR61
NCBI GenBank: NM_019074 | NP_061947.1
SwissProt: Q9NR61

Target

Target: Human DLL4
Antigen Species: Human
Epitope: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344).
Gene Name: DLL4