CYP3A4 / Cytochrome P450 3A4 Antibody (Biotin)

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Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C498663-50

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Description: Cytochrome P450 3A4 antibody LS-C498663 is a biotin-conjugated rabbit polyclonal antibody to human Cytochrome P450 3A4 (CYP3A4). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Cyp3a3 | CYP3A4 | CYPIIIA3 | CYPIIIA4 | Cytochrome P450 3A3 | Cytochrome P450 3A4 | CP33 | CP34 | CYP3A | Cytochrome P450 NF-25 | HLP | NF-25 | p450C3 | Cytochrome P450 HLp | Cytochrome P450-PCN1 | Glucocorticoid-inducible P450 | p450-III, steroid inducible | p450PCN1
UniProt Number: P08684
SwissProt: P08684

Target: Human CYP3A4 / Cytochrome P450 3A4
Antigen Species: Human
Epitope: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).
Gene Name: CYP3A4

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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