LSBio
CXCR3 Antibody (clone 2AR1)

CXCR3 Antibody (clone 2AR1)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Functional Assay, Immunohistochemistry (general), Neutralization
Reactivity:Human
Format:Lyophilized
See all Human CXCR3 antibodies →
$982.00each
Catalog Number: LS-C6283-100

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Overview

Description
CXCR3 antibody LS-C6283 is an unconjugated mouse monoclonal antibody to human CXCR3. Validated for Flow, Func, IHC and Neut. Cited in 2 publications.
Application
FC, Func, IHC, Neut
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
C-x-c chemokine receptor 3 | CD183 antigen | CKR-L2 | CXCR-3 | CXCR3 | CMKAR3 | CD182 | CD183 | Cxcr3a | GPR9 | IP-10 receptor | IP10-R | Mig receptor | MigR | Mig-R | Chemokine (C-X-C) receptor 3 | CXC-R3 | Cxcr3b | G protein-coupled receptor 9 | IP10 receptor
Recommended Dilution: FC
5 - 10 µg/ml
Recommended Dilution: IHC
10 µg/ml
UniProt Number
P49682
SwissProt
P49682

Target

Target
Human CXCR3
Antigen Species
Human
Epitope
Recognizes human CXCR3. Reacts specifically with CXCR3 transfectants and not the parental cell line using FACS analysis. Does not cross-react with CXCR1, CXCR2, CXCR4 or transfectants.
Gene Name
CXCR3

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
2AR1
Isotype
IgG1

Immunogen

Immunogen
CXCR3 transfected NS0 cells.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from PBS, pH 6.8, 5% Trehalose
Preservative
No
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. Denkert C, Loibl S, Noske A, Roller M, Mller BM, Komor M, Budczies J, Darb-Esfahani S, Kronenwett R, Hanusch C, von Trne C, Weichert W, Engels K, Solbach C, Schrader I, Dietel M, von Minckwitz G. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010;28:105-13.

PubMed: 19917869


Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Mikucki ME, Fisher DT, Matsuzaki J, Skitzki JJ, Gaulin NB, Muhitch JB, Ku AW, Frelinger JG, Odunsi K, Gajewski TF, Luster AD, Evans SS. Nature communications. 2015;6:7458.

PubMed: 26109379 · PMC: PMC4605273

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