LSBio
IHC-plus™ Polyclonal Rabbit anti-Human CXCR3 Antibody (IHC, IF, WB)

Anti-CXCR3 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ Polyclonal Rabbit anti-Human CXCR3 Antibody (IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$556.00each
Catalog Number: LS-B10183-0.05

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Overview

Description
CXCR3 antibody LS-B10183 is an unconjugated rabbit polyclonal antibody to CXCR3 from human. It is reactive with human, mouse and rat. Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Application
ELISA, ICC, IF, IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
C-x-c chemokine receptor 3 | CD183 antigen | CKR-L2 | CXCR-3 | CXCR3 | CMKAR3 | CD182 | CD183 | Cxcr3a | GPR9 | IP-10 receptor | IP10-R | Mig receptor | MigR | Mig-R | Chemokine (C-X-C) receptor 3 | CXC-R3 | Cxcr3b | G protein-coupled receptor 9 | IP10 receptor
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: WB
1 - 2 µg/ml
UniProt Number
P49682
SwissProt
P49682

Target

Target
CXCR3
Antigen Species
Human
Specificity
CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.
Epitope
CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.
Gene Name
CXCR3

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A 19 amino acid peptide near the C-Terminus of human CXCR3 . The immunogen is located within the last 50 amino acids of CXCR3.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS containing 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

CXCR3 regulates CD4+ T cell cardiotropism in pressure overload-induced cardiac dysfunction. Ngwenyama N, Salvador AM, Velázquez F, Nevers T, Levy A, Aronovitz M, Luster AD, Huggins GS, Alcaide P. JCI insight. 2019 April;4:pii: 125527.

PubMed: 30779709 · PMC: PMC6483643


Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFN?/CXCL10-dependent peripheral T cell recruitment in humanized murine model. Floriana Cremasco, Elena Menietti, Dario Speziale, Johannes Sam, Stefano Sammicheli, Marine Richard, Ahmet Varol, Christian Klein, Pablo Umana, Marina Bacac, Sara Colombetti, Mario Perro. PloS one. 2021 Jan;16:e0241091.

PubMed: 33406104 · PMC: PMC7787458


Microparticle-Delivered Cxcl9 Prolongs Braf Inhibitor Efficacy in Melanoma. Gabriele Romano, Francesca Paradiso, Peng Li, Pooja Shukla, Lindsay N Barger, Olivia El Naggar, John P Miller, Roger J Liang, Timothy L Helms, Alexander J Lazar, Jennifer A Wargo, Francesca Taraballi, James C Costello, Lawrence N Kwong. Cancer immunology research. 2023 May;11:558-569.

PubMed: 36820825 · PMC: PMC10159986

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