LSBio
Complement C3d Antibody (clone 053A-1149.3.1.4 (also known as 1003))

Complement C3d Antibody (clone 053A-1149.3.1.4 (also known as 1003))

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Western Blot
Reactivity:Human
Format:Liquid
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$540.00each
Catalog Number: LS-C44975-0.1

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Overview

Description
Complement C3d antibody LS-C44975 is an unconjugated mouse monoclonal antibody to human Complement C3d. Validated for ELISA, Flow, IHC and WB.
Application
ELISA, FC, IHC, IHC-F, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: WB
1:5000

Target

Target
Human Complement C3d
Antigen Species
Human
Epitope
Specific for human complement component 3d (C3d), a 33kD polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
053A-1149.3.1.4 (also known as 1003)
Isotype
IgG1

Immunogen

Immunogen
Purified C3d from human plasma.
Immunogen Type
Native Protein (Purified from Natural Source)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
BBS, 0.1% Sodium Azide
Concentration
1.14 mg/mL
Volume
0.1 Milliliter
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
bbs

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.