LSBio
Complement C3 Antibody (clone 053A-514.3.1.4)

Complement C3 Antibody (clone 053A-514.3.1.4)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Human
Format:Liquid
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$540.00each
Catalog Number: LS-C44997-0.1

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Overview

Description
Complement C3 antibody LS-C44997 is an unconjugated mouse monoclonal antibody to human Complement C3. Validated for ELISA, Flow and IHC.
Application
ELISA, FC, IHC, IHC-F
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
AHUS5 | ARMD9 | C3 | Complement component C3 | CPAMD1 | Complement C3 | ASP | Complement component 3
UniProt Number
P01024
NCBI GenBank
NM_000064 | NP_000055.2
SwissProt
P01024

Target

Target
Human Complement C3
Antigen Species
Human
Epitope
Specific for human complement component 3d (C3d) neoantigen, a 33kD polypeptide fragment generated over the course of complement activation in which where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
Gene Name
C3

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
053A-514.3.1.4
Isotype
IgG1

Immunogen

Immunogen
Purified human C3d (neoantigen).
Immunogen Type
Native Protein (Purified from Natural Source)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
BBS, 0.1% Sodium Azide
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
bbs

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.