IHC of p-Chk1 (S345) pAb in paraffin-embedded human breast carcinoma tissue.
CHEK1 / CHK1 Antibody (phospho-Ser345)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$335.00each
Catalog Number: LS-C177888-50
Catalog Number: LS-C177888
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- Description
- CHK1 antibody LS-C177888 is an unconjugated rabbit polyclonal antibody to CHK1 (CHEK1) (pSer345) from human. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 1 publication.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CHEK1 | CHK1 checkpoint homolog | Cell cycle checkpoint kinase | Checkpoint kinase 1 | CHK1 | Chk1-S | Protein kinase chk1 | Checkpoint kinase-1
- Recommended Dilution: IHC-P
- 1:50 - 1:200
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- O14757
- NCBI GenBank
- NM_001274 | NP_001265.2
- SwissProt
- O14757
Target
- Target
- Human CHEK1 / CHK1
- Antigen Species
- Human
- Epitope
- Human CHK1
- Gene Name
- CHEK1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Synthetic phosphopeptide around pSer345 of human CHK1
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.2, 0.05% Sodium Azide
- Concentration
- 1 mg/mL
- Volume
- 50 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Small molecule targeting of transcription-replication conflict for selective chemotherapy. Long Gu, Min Li, Caroline M Li, Pouya Haratipour, Robert Lingeman, Jennifer Jossart, Margarita Gutova, Linda Flores, Caitlyn Hyde, Nikola Kenjic, Haiqing Li, Vincent Chung, Hongzhi Li, Brett Lomenick, Daniel D Von Hoff, Timothy W Synold, Karen S Aboody, Yilun Liu, David Horne, Robert J Hickey, J Jefferson P Perry, Linda H Malkas. Cell Chemical Biology. 2023 October;30:1235-1247.e6. PubMed: 37531956