
Positive WB detected in:HEK293 whole cell lysate,Hela whole cell lysate,Mouse heart tissue,Mouse liver tissue,Mouse brain tissue,Mouse kidney tissue;All lanes: CDH2 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 100,98 kDa;Observed band size: 100 kDa;
CDH2 / N Cadherin Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C498581-50
Catalog Number: LS-C498581
For bulk orders or custom formulations:
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- Description
- N Cadherin antibody LS-C498581 is an unconjugated rabbit polyclonal antibody to N Cadherin (CDH2) from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
- Application
- ELISA, IF, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CDH2 | CDw325 | CDHN | Cadherin-2 | CD325 | CD325 antigen | N Cadherin | N-cadherin | NCAD | Neural cadherin | N-cadherin 1 | Neural-cadherin
- UniProt Number
- P19022
- NCBI GenBank
- NM_001792 | NP_001783.2
- SwissProt
- P19022
Target
- Target
- Human CDH2 / N Cadherin
- Antigen Species
- Human
- Epitope
- Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).
- Gene Name
- CDH2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Cadherin-2 protein (746-906AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
