Western blot analysis on normal human spleen lysate probed with Rabbit anti-Human CD193 (RABBIT ANTI HUMAN CD193).

CCR3 Antibody (C-Terminus)

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Antibody:	Rabbit Polyclonal
Applications:	Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:	Human
Format:	Liquid

$436.00each

Catalog Number: LS-C42330-0.1

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Description: CCR3 antibody LS-C42330 is an unconjugated rabbit polyclonal antibody to human CCR3 (C-Terminus). Validated for IF, IHC and WB.
Application: IF, IHC, IHC-P, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: C-C chemokine receptor type 3 | B-chemokine receptor | CD193 | CD193 antigen | CCR3 | Chemokine c-c motif receptor 3 | C-C chemokine receptor 3 | CKR3 | CC-CKR-3 | CCR-3 | CMKBR3 | Eosinophil eotaxin receptor | Eotaxin receptor | C-C CKR-3 | CC chemokine receptor 3
Recommended Dilution: IHC-P: 10 µg/ml
UniProt Number: P51677
NCBI GenBank: NM_001837 | NP_001828.1
SwissProt: P51677

Target: Human CCR3
Antigen Species: Human
Epitope: Recognizes human CD193, otherwise known as CC chemokine receptor 3 (CCR3), a seven-helix transmembrane G-protein coupled receptor which, along with and, acts as a principal receptor for the fusion and entry of HIV into target cells. CD193 is expressed by eosinophils, basophils, mast cells, microglia, Th2 helper cells and some epithelial cells. CD193 acts as a receptor for several CC chemokines including monocyte chemoattractant proteins (MCP) -1, -2, -3 and -4, MIP-1a, MIP-1β, and RANTES. The eotaxin subgroup of CC chemokines act as specific agonists for CD193, and this interaction has become a focus area for studies into the infection of microglia by HIV and allergy research. Has been used successfully for the detection of human CD193 by immunohistochemistry on formalin fixed, paraffin embedded intervertebral disc tissue.
Gene Name: CCR3

Immunogen: Synthetic peptide corresponding to a 14 amino acid sequence located near human CD193 C-Terminus.
Immunogen Type: Synthetic Peptide (Linear)

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS