Positive WB detected in:Hela whole cell lysate,HEK293 whole cell lysate,MCF-7 whole cell lysate,HepG2 whole cell lysate,Mouse brain tissue;All lanes: BUB3 antibody at 3.4ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 38,37 kDa;Observed band size: 38,37 kDa;

BUB3 Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity:	Human, Mouse
Format:	Liquid

$300.00each

Catalog Number: LS-C498467-50

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Overview

Description: BUB3 antibody LS-C498467 is an unconjugated rabbit polyclonal antibody to BUB3 from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB.
Application: ELISA, IHC, WB
Reactivity: Hu, Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Budding uninhibited by benomyl | BUB3 | HBUB3 | BUB3L | Mitotic checkpoint component
UniProt Number: O43684
NCBI GenBank: NM_004725 | NP_004716.1
SwissProt: O43684

Target

Target: Human BUB3
Antigen Species: Human
Epitope: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Gene Name: BUB3