AUTL1 / ATG4C Antibody (Biotin)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C501225-50

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Description: ATG4C antibody LS-C501225 is a biotin-conjugated rabbit polyclonal antibody to human ATG4C (AUTL1). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: AUTL3 | APG4-C | APG4C | AUTL1 | Autophagin-3 | APG4 autophagy 4 homolog C | ATG4C | Cysteine protease ATG4C
UniProt Number: Q96DT6
NCBI GenBank: NM_032852 | NP_116241.2
SwissProt: Q96DT6

Target: Human AUTL1 / ATG4C
Antigen Species: Human
Epitope: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Gene Name: ATG4C

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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