Western blot analysis of RUNX1 expression in THP1 (A); Jurkat (B) whole cell lysates.
AML1 / RUNX1 Antibody (Internal)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Chicken, Human, Mouse, Pig, Rat |
| Format: | Liquid |
$261.00each
Catalog Number: LS-C353932-30
Catalog Number: LS-C353932
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- Description
- RUNX1 antibody LS-C353932 is an unconjugated rabbit polyclonal antibody to RUNX1 (AML1) (Internal) from human. It is reactive with human, mouse, rat and other species. Validated for IF, IHC and WB. Cited in 2 publications.
- Application
- IF, IHC, IHC-P, WB
- Reactivity
- Ck, Hu, Ms, Por, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AMLCR1 | Aml1 oncogene | AML1 | AML1-EVI-1 | CBF-alpha-2 | CBFA2 | Acute myeloid leukemia 1 | EVI-1 | PEBP2A2 | PEA2-alpha B | AML1-EVI-1 fusion protein | Oncogene AML-1 | PEBP2-alpha B | PEBP2aB | RUNX1
- Recommended Dilution: IF/ICC
- 1:100 - 1:500
- Recommended Dilution: IHC-P
- 1:100 - 1:200
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- Q01196
- NCBI GenBank
- NM_001754 | NP_001745.2
- SwissProt
- Q01196
Target
- Target
- Human AML1 / RUNX1
- Antigen Species
- Human
- Epitope
- Recognizes endogenous levels of RUNX1 protein.
- Gene Name
- RUNX1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within the central region of human RUNX1.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
- Volume
- 30 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Aliquot to avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Runt related transcription factor-1 plays a central role in vessel co-option of colorectal cancer liver metastases. Miran Rada, Audrey Kapelanski-Lamoureux, Stephanie Petrillo, Sébastien Tabariès, Peter Siegel, Andrew R Reynolds, Anthoula Lazaris, Peter Metrakos. Communications biology. 2021 Aug;4:950.
PubMed: 34376784 · PMC: PMC8355374
The molecular mechanisms underlying neutrophil infiltration in vessel co-opting colorectal cancer liver metastases. Miran Rada, Nour Hassan, Anthoula Lazaris, Peter Metrakos. Frontiers in oncology. 2022 November;12:1004793.
PubMed: 36330498 · PMC: PMC9623070