AML1 / RUNX1 Antibody
Catalog Number: LS-C417588
2 sizes / from $312.00
Antibody: Rabbit Polyclonal
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
IHC-plus™ AML1 / RUNX1 Antibody (aa150-250)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$470.00each
Catalog Number: LS-B13948-50
Catalog Number: LS-B13948
For bulk orders or custom formulations:
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- Description
- RUNX1 antibody LS-B13948 is an unconjugated rabbit polyclonal antibody to RUNX1 (AML1) (aa150-250) from human. It is reactive with human, mouse and rat. Validated for ICC, IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
- Application
- ICC, IF, IHC, IHC-P, IP, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AMLCR1 | Aml1 oncogene | AML1 | AML1-EVI-1 | CBF-alpha-2 | CBFA2 | Acute myeloid leukemia 1 | EVI-1 | PEBP2A2 | PEA2-alpha B | AML1-EVI-1 fusion protein | Oncogene AML-1 | PEBP2-alpha B | PEBP2aB | RUNX1
- Recommended Dilution: IF/ICC
- 1:50 - 1:200
- Recommended Dilution: IHC
- 1:50 - 1:100
- Recommended Dilution: IHC-P
- 1:100
- Recommended Dilution: IP
- 1:20 - 1:100
- Recommended Dilution: WB
- 1:500 - 1:2000
- UniProt Number
- Q01196
- NCBI GenBank
- NM_001754 | NP_001745.2
- SwissProt
- Q01196
Target
- Target
- AML1 / RUNX1
- Antigen Species
- Human
- Specificity
- Human, mouse, rat AML1 / RUNX1
- Epitope
- Human AML1 / RUNX1
- Gene Name
- RUNX1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- A synthetic peptide of human RUNX1.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
TNF-a signaling regulates RUNX1 function in endothelial cells. Hannah A B Whitmore, Dhanesh Amarnani, Michael O'Hare, Santiago Delgado-Tirado, Lucia Gonzalez-Buendia, Miranda An, Julien Pedron, John H Bushweller, Joseph F Arboleda-Velasquez, Leo A Kim. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020 November.
PubMed: 33135824 · PMC: PMC7821222
Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy. Santiago Delgado-Tirado, Dhanesh Amarnani, Guannan Zhao, Elizabeth J Rossin, Dean Eliott, John B Miller, Whitney A Greene, Leslie Ramos, Said Arevalo-Alquichire, David Leyton-Cifuentes, Lucia Gonzalez-Buendia, Daniela Isaacs-Bernal, Hannah A B Whitmore, Natalia Chmielewska, Brandon V Duffy, Eric Kim, Heuy-Ching Wang, Jose M Ruiz-Moreno, Leo A Kim, Joseph F Arboleda-Velasquez. Scientific reports. 2020 November;10:20554.
PubMed: 33257736 · PMC: PMC7705016
Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. Michael O'Hare, Dhanesh Amarnani, Hannah A B Whitmore, Miranda An, Claudia Marino, Leslie Ramos, Santiago Delgado-Tirado, Xinyao Hu, Natalia Chmielewska, Anita Chandrahas, Antonia Fitzek, Fabian Heinrich, Stefan Steurer, Benjamin Ondruschka, Markus Glatzel, Susanne Krasemann, Diego Sepulveda-Falla, David Lagares, Julien Pedron, John H Bushweller, Paul Liu, Joseph F Arboleda-Velasquez, Leo A Kim. The American journal of pathology. 2021 Jul;;191:1193-1208.
PubMed: 33894177 · PMC: PMC8059259
Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis. Santiago Delgado-Tirado, Lucia Gonzalez-Buendia, Miranda An, Dhanesh Amarnani, Daniela Isaacs-Bernal, Hannah Whitmore, Said Arevalo-Alquichire, David Leyton-Cifuentes, Jose M Ruiz-Moreno, Joseph F Arboleda-Velasquez, Leo A Kim. Ophthalmology science. 2022 September;2.
PubMed: 36213726 · PMC: PMC9536424
