LSBio
ACCN3 / ASIC3 Antibody (aa56-73)

WB of ACCN3 / ASIC3 antibody. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Testis Tissue Lysate. Lane 3: U87 Cell Lysate. Lane 4: NEURO Cell Lysate. Lane 5: SMMC Cell Lysate.

ACCN3 / ASIC3 Antibody (aa56-73)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Western Blot
Reactivity:Human, Mouse, Non-Human Primate, Rat
Format:Lyophilized
See all Human ACCN3 / ASIC3 antibodies →
$480.00each
Catalog Number: LS-C313073-100

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Overview

Description
ASIC3 antibody LS-C313073 is an unconjugated rabbit polyclonal antibody to ASIC3 (ACCN3) (aa56-73) from human. It is reactive with human, mouse, rat and other species. Validated for WB. Cited in 1 publication.
Application
WB
Reactivity
Hu, Ms, NHP, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Acid-sensing ion channel 3 | Acid-sensing ion channel | ASIC3 | ACCN3 | HASIC3 | HTNaC1 | Modulatory subunit of ASIC2a | SLNAC1 | DRASIC | Testis sodium channel 1 | TNaC1
UniProt Number
Q9UHC3
SwissProt
Q9UHC3

Target

Target
Human ACCN3 / ASIC3
Antigen Species
Human
Epitope
Expressed by sensory neurons. Strongly expressed in brain, spinal chord, lung, lymph nodes, kidney, pituitary, heart and testis. .
Gene Name
ASIC3

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
A synthetic peptide corresponding to a sequence at the N-Terminus of human ASIC3(56-73 aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
Concentration
0.5 mg/mL
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Recommended Storage Buffer
NaCl
Endomorphins potentiate acid-sensing ion channel currents and enhance the lactic acid-mediated increase in arterial blood pressure: effects amplified in hindlimb ischaemia. Mohamed Farrag, Julie K Drobish, Henry L Puhl, Joyce S Kim, Paul B Herold, Marc P Kaufman, Victor Ruiz-Velasco. The Journal of physiology. 2017 December;595:7167-7183. PubMed: 29044528 PMC: PMC5709321

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