Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (800) 227-6666


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B16117-100 100 µl (1 mg/ml) $460 
ACTH Antibody - Human Anterior Pituitary: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ Monoclonal Mouse anti‑Human ACTH Antibody (IHC) LS‑B16117

PathPlus™ Monoclonal Mouse anti‑Human ACTH Antibody (IHC) LS‑B16117

Note: This antibody replaces LS-C744444
Antibody:
ACTH Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B16117-100
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
ACTH Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone. Part of the hypothalamic-pituitary-adrenal axis, it stimulates the secretion of steroid hormones from the adrenal cortex. It also exerts effects on osteoblasts. ACTH is expressed and secreted by corticotropes in the anterior pituitary gland and is also expressed at lower levels in the brain, adrenal medulla, skin, and placenta and at higher levels in ACTH-secreting tumors. Staining is used to identify ACTH-secreting tumors such as pituitary adenomas and nonpituitary tumors such as pancreatic neuroendocrine neoplasms and pancreatic acinar cell carcinomas and pancreatoblastomas. References: J Mol Endocrinol. 2016;56(4):T135-T156. doi: 10.1530/JME-15-0257;Microsc Res Tech. 2003;61(3):308-314. PMID: 12768546;J Neuroendocrinol. 2008;20(6):692-699. doi: 10.1111/j.1365-2826.2008.01709.x;Am J Surg Pathol. 2015;39(3):374-382. doi: 10.1097/PAS.0000000000000340;Ann N Y Acad Sci. 2009;1163:93-100. doi: 10.1111/j.1749-6632.2009.04434.x.
Target
Human ACTH
Synonyms
ACTH
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic ACTH-Adrenocorticotropin (ACTH)
Applications
  • IHC (1:200 - 1:400)
  • IHC - Paraffin (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Use Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH 8.0 Recommended IHC controls tissues are Pituitary. Resulting localization is Cytoplasmic
Presentation
0.5% BSA,  0.1% Kathon, Tris-Buffered Saline, DI H2O and 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

Validation

ACTH Antibody - Human Anterior Pituitary: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Anterior Pituitary: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Anterior Pituitary: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ ACTH Antibody for IHC LS-B16117 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/31/2024