LSBio
Monoclonal Mouse anti-Dog LAMP2 / CD107b Antibody (clone AC17, IF, WB)

Monoclonal Mouse anti-Dog LAMP2 / CD107b Antibody (clone AC17, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
Reactivity:Dog
Format:Liquid
See all Dog LAMP2 / CD107b antibodies →
$363.00each
Catalog Number: LS-C188336-0.1

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Overview

Description
CD107b antibody LS-C188336 is an unconjugated mouse monoclonal antibody to dog CD107b (LAMP2). Validated for Flow, IF, IP and WB.
Application
FC, IF, IP, WB
Reactivity
Can
Nonreactive Species
Mouse, Rat
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD107b | CD107b antigen | LAMPB | LGP110 | LAMP2 | LAMP-2
Recommended Dilution: WB
1:100 - 1:500
UniProt Number
P13473
SwissProt
P13473

Target

Target
Dog LAMP2 / CD107b
Antigen Species
Dog
Epitope
Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.
Gene Name
LAMP2

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
AC17
Isotype
IgG1

Immunogen

Immunogen
MDCK (Madin-Darby Canine Kidney) cells.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.