LAMP2 / CD107b Antibody (clone AC17, FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Dog |
| Format: | Liquid |
$540.00each
Catalog Number: LS-C188337-0.1
Catalog Number: LS-C188337
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- Description
- CD107b antibody LS-C188337 is an FITC-conjugated mouse monoclonal antibody to dog CD107b (LAMP2). Validated for Flow.
- Application
- FC
- Reactivity
- Can
- Nonreactive Species
- Mouse, Rat
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD107b | CD107b antigen | LAMPB | LGP110 | LAMP2 | LAMP-2
- Recommended Dilution: FC
- 0.0423611111111111
- UniProt Number
- P13473
- NCBI GenBank
- NM_013995 | NP_054701.1
- SwissProt
- P13473
Target
- Target
- Dog LAMP2 / CD107b
- Antigen Species
- Dog
- Epitope
- Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.
- Gene Name
- LAMP2
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- AC17
- Isotype
- IgG1
Immunogen
- Immunogen
- MDCK (Madin-Darby Canine Kidney) cells.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Fluorescein Isothiocyanate
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide, 1% BSA
- Concentration
- 0.1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS