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Anti-DERL1 / Derlin 1 Antibody (aa200-251) IHC-plus™ LS-B494

Note: This antibody replaces LS-C2647


Wt. Vol. Conc. Price
- 50 µl 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C141165 Biotin Conjugated
LS-C141166 DY650 Conjugated
LS-C141167 DY488 Conjugated
LS-C141169 DY550 Conjugated

Most Popular DERL1 / Derlin 1 Antibodies

Anti-DERL1 / Derlin 1 Antibody (aa200-251) IHC-plus™ LS-B494
Rabbit Polyclonal to Human DERL1 / Derlin 1
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-DERL1 / Derlin 1 Antibody (aa224-251) IHC-plus™ LS-B9896
Rabbit Polyclonal to Human DERL1 / Derlin 1
Human, Mouse
IHC - Paraffin, Western blot, Flow Cytometry
Immunohistochemistry Image
Anti-DERL1 / Derlin 1 Antibody (C-Terminus, AP) LS-C276740
Rabbit Polyclonal (IgG) to Human DERL1 / Derlin 1
Human, Mouse
Western blot, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human DERL1 / Derlin 1
IHC - Paraffin, Western blot (applications tested for the base form of this product only)


Human DERL1 / Derlin 1
Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 - 10 µg/ml)
  • Western blot (1:1000 - 1:5000)
  • (applications tested for the base form of this product only)

Specificity and Use

DERL1 / Derlin 1 antibody was raised against a synthetic peptide made to the C-terminal region of the human Derlin-1 protein sequence (between residues 200-251) Percent identity by BLAST analysis: Human (100%).
Immunohistochemistry: LS-B494 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B494 was determined to be 5-10 ug/ml.


Contains 0.1% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About DERL1 / Derlin 1

Q9BUN8 NM_024295 NP_077271.1

DERL1 Antibody, DER1 Antibody, Der1-like protein 1 Antibody, Derlin-1 Antibody, DERtrin-1 Antibody, PRO2577 Antibody, DER-1 Antibody, Derlin 1 Antibody

Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate.


Anti-DERL1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B494 concentration 10 ug/ml. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/25/2016

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