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Catalog Number	Size	Price
LS-C44994-0.1	0.1 mg (1.08 mg/ml)	$568

Monoclonal Mouse anti‑Human Complement C8 Antibody (clone 056B‑373, IHC, WB) LS‑C44994

Name: Anti-Complement C8 Antibody | Mouse anti-Human Monoclonal | LSBio
Brand: Lifespan BioSciences
SKU: LS-C44994-0.1
Price: 568.0000 USD
Availability: InStock

Submit Review LSBio Guarantee

Note: This antibody replaces LS-C123310

Antibody:

Complement C8 Mouse anti-Human Monoclonal (056B-373) Antibody

Application:

IHC, IHC-Fr, WB, Flo, ELISA

Reactivity:

Human

Format:

Unconjugated, Unmodified

$568

LS-C44994-0.1

Toll Free North America

206-374-1102

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

Complement C8 Mouse anti-Human Monoclonal (056B-373) Antibody

Application:

IHC, IHC-Fr, WB, Flo, ELISA

Reactivity:

Human

Format:

Unconjugated, Unmodified

Specifications

Description

Complement C8 antibody LS-C44994 is an unconjugated mouse monoclonal antibody to human Complement C8. Validated for ELISA, Flow, IHC and WB.

Target

Human Complement C8

See All Complement C8 Antibodies

Host

Mouse

Reactivity

Human (tested or 100% immunogen sequence identity)

Clonality

IgG1 Monoclonal

Clone

056B-373

Conjugations

Unconjugated

Purification

Protein A purified

Modifications

Unmodified

Immunogen

Purified human C8.

Specificity

Recognizes complement component 8 (C8), a 151 kD member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.

Applications

IHC
IHC - Frozen
Western blot
Flow Cytometry
ELISA

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Presentation

BBS, 0.1% Sodium Azide

Storage

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee