Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
COL9A1 / Collagen IX is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis.
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with COL9A1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
COL9A1 Antibody western blot of MCF-7 cell line and mouse eyeball,rat eyeball tissue lysates (35 ug/lane). The COL9A1 antibody detected the COL9A1 protein (arrow).
Western blot of anti-COL9A1 Antibody in 293 cell line lysates (35 ug/lane). COL9A1(arrow) was detected using the purified antibody.
COL9A1 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The COL9A1 antibody detected the COL9A1 protein (arrow).
Requested From: United States
Date Requested: 2/20/2017