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Anti-CAND2 / TIP120B Antibody (C-Terminus) IHC-plus™ LS-B348

Note: This antibody replaces LS-C19123

Ordering

Wt. Vol. Conc. Price
- 50 µl 85 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Orders@LSBio.com
 

Most Popular CAND2 / TIP120B Antibodies

Anti-CAND2 / TIP120B Antibody (C-Terminus) IHC-plus™ LS-B348
Rabbit Polyclonal to Human CAND2 / TIP120B
Human
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CAND2 / TIP120B Antibody (N-Terminus) LS-C81574
Rabbit Polyclonal (IgG) to Human CAND2 / TIP120B
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Zebrafish
Western blot
Unconjugated
Western blot Image
Anti-CAND2 / TIP120B Antibody (aa1223-1236) LS-C127212
Rabbit Polyclonal to Human CAND2 / TIP120B
Human, Horse, Pig
Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed Publications Publications (3)
Rabbit Polyclonal to Human CAND2 / TIP120B
Human
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human CAND2 / TIP120B
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Delipidated and defibrinated
Unmodified

Applications

  • IHC - Paraffin (1:500)
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation
  • ELISA (1:2000 - 1:10000)

Specificity and Use

CAND2 / TIP120B antibody was raised against synthetic peptide from human CAND2 / TIP120B.
C-Terminus
Amino acids 1130-1143 of Human CAND2/TIP120B (C-terminal) coupled to KLH.
Immunohistochemistry: LS-B348 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B348 was determined to be 1:500.

Packaging

0.01% sodium azide.
Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
For research use only.

Publications (3)

1
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Liu J, Furukawa M, Matsumoto T, Xiong Y. Molecular cell. 2002 10:1511-8. [PubMed:12504025]
2
AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis. Cheng Y, Dai X, Zhao Y. Plant physiology. 2004 135:1020-6. [PubMed:15181201] [PMC:PMC514136]
3
Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation. Feng S, Shen Y, Sullivan JA, Rubio V, Xiong Y, Sun TP, Deng XW. The Plant cell. 2004 16:1870-82. [PubMed:15208391] [PMC:PMC514167]

About CAND2 / TIP120B

O75155 NP_036430.1

CAND2 Antibody, KIAA0667 Antibody, p120 CAND2 Antibody, TBP interacting protein Antibody, TIP120B Antibody, TBP-interacting protein 120B Antibody, Tp120b Antibody

Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.

Immunohistochemistry

Immunohistochemistry
Anti-CAND2 / TIP120B antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B348 dilution 1:500.
 

Requested From: United States
Date Requested: 12/9/2016

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