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Anti-BRCC45 / BRE Antibody (N-Terminus) IHC-plus™ LS-B2700

Note: This antibody replaces LS-C34743

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular BRCC45 / BRE Antibodies

Anti-BRCC45 / BRE Antibody (N-Terminus) IHC-plus™ LS-B2700
Rabbit Polyclonal (IgG) to Human BRCC45 / BRE
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-BRCC45 / BRE Antibody IHC-plus™ LS-B4837
Rabbit Polyclonal to Human BRCC45 / BRE
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-BRCC45 / BRE Antibody (Internal) IHC-plus™ LS-B12472
Rabbit Polyclonal (IgG) to Human BRCC45 / BRE
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human BRCC45 / BRE
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human BRCC45 / BRE
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (1 - 2 µg/ml)
  • ELISA

Specificity and Use

BRCC45 / BRE antibody was raised against synthetic peptide from human BRE.
LS-E30389 - Liquid - 50 µg - $145.00
N-Terminus
an 18 amino acid peptide from near the amino terminus of human BRCC45
Immunohistochemistry: LS-B2700 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2700 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About BRCC45 / BRE

Q9NXR7 NM_004899 NP_004890.2

BRE Antibody, BRCA1-A complex subunit BRE Antibody, BRCC45 Antibody, BRCC4 Antibody

Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

Immunohistochemistry

Immunohistochemistry
Anti-BRE antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2700 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of BRCC45 in human brain tissue with BRCC45 antibody at 20 ug/ml.

Western blot

Western blot
Western blot of TRIM25 in HeLa cell lysate in (A) the absence and (B) absence of blocking peptide with TRIM25 antibody at 1 ug/ml.
 

Requested From: United States
Date Requested: 12/4/2016

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