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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BMP2K / BIKE Antibody (N‑Terminus) IHC‑plus™ LS‑A6938
BIKE antibody LS-A6938 is an unconjugated rabbit polyclonal antibody to human BIKE (BMP2K). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A6938-50
50 µg (1 mg/ml)
$425
In Stock for Immediate Shipment

Popular BMP2K / BIKE Products

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Anti-BMP2K antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B783 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, ELISA
BMP2K antibody LS-C110693 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Guinea pig, Drosophila
Applications: Western blot
Western blot analysis of BIKE expression in A549 (A); NIH3T3 (B); PC12 (C) whole cell lysates.
Species: Human, Mouse, Rat
Applications: Western blot

Product Description

BIKE antibody LS-A6938 is an unconjugated rabbit polyclonal antibody to human BIKE (BMP2K). Validated for IHC. Tested on 20 paraffin-embedded human tissues.

Specifications

Target
Human BMP2K / BIKE
Synonyms
BMP2K, BMP2 inducible kinase, BIKE, BMP-2-inducible protein kinase, BMP-2 inducible kinase, HRIHFB2017, Bike kinase
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
BMP2K / BIKE antibody was raised against synthetic 15 amino acid peptide from N-terminus of human BMP2K. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Mouse (93%); Chicken, Zebrafish (87%).
Blocking Peptide
LS-E29204 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A6938. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human BMP2K. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Usage
Antigen retrieval requires Proteinase K treatment.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About BMP2K / BIKE
BMP2K / BIKE is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Q9NSY1 NM_017593 NP_060063.2


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Images

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BMP2K antibody LS-A6938 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 10/18/2018

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