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Anti-AHR Antibody (N-Terminus) IHC-plus™ LS-A3005

Note: This antibody replaces LS-C63830, LS-C42630

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities
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Rabbit Polyclonal to Human AHR
Human
IHC - Paraffin
Unconjugated

Details

Human AHR
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey, Horse (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (6 µg/ml)

Specificity and Use

AHR antibody was raised against synthetic 16 amino acid peptide from N-terminus of human Aryl Hydrocarbon Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey, Horse (94%); Marmoset, Bovine (88%); Bat, Dog, Hamster, Panda, Guinea pig (81%).
LS-E28669 - Liquid - 50 µg - $145.00
N-Terminus
Human Aryl Hydrocarbon Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry: LS-A3005 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A3005 was determined to be 6 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About AHR

P35869 NM_001621 NP_001612.1

AHR Antibody, Ah receptor Antibody, AH-receptor Antibody, Aryl hydrocarbon receptor Antibody, BHLHe76 Antibody, Aromatic hydrocarbon receptor Antibody

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.

Immunohistochemistry

Immunohistochemistry
Anti-Aryl Hydrocarbon Receptor antibody LS-A3005 IHC of human respiratory epithelium and bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 9/29/2016

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