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Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.
Gene Name: | NME/NM23 family member 8 |
Synonyms: | NME8, CILD6, Sperm-specific thioredoxin 2, SPTRX2, NM23-H8, NME/NM23 family member 8, Sptrx-2, TXNDC3 |
Target Sequences: | NM_016616 NP_057700.3 Q8N427 |
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