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Unfortunately, the antibody LS-C225015 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TRAF3IP2 / ACT1 Antibodies

TRAF3 interacting protein 2

Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB associates with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKa, IKKb, and IKKg. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kB activator 1). CIKS directly interacts with IKKg. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.

Gene Name: TRAF3 interacting protein 2
Synonyms: TRAF3IP2 Antibody, C6orf2 Antibody, C6orf4 Antibody, C6orf5 Antibody, CIKS Antibody, DKFZP586G0522 Antibody, Connection to IKK and SAPK/JNK Antibody, ACT1 Antibody, Adapter protein CIKS Antibody, NFkB-activating protein ACT1 Antibody, PSORS13 Antibody, TRAF3-interacting protein 2 Antibody, C6orf6 Antibody, TRAF3 interacting protein 2 Antibody
Target Sequences: NM_147200 NP_671733.1 O43734
 TRAF3IP2 / ACT1 Feature Table
Featured Image

Featured TRAF3IP2 / ACT1 Antibody

LS-B5448 is a mouse monoclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.


TRAF3IP2 / ACT1 Antibodies (20)

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
TRAF3IP2 / ACT1 Mouse IgG2a,k Monoclonal 4A3 Unconjugated Human IHC-P, IF, WB, ELISA No Primary
Anti-TRAF3IP2 / ACT1 Antibody (clone 4A3) IHC-plus™ LS-B5448
IHC Image
IF Image
Mouse Monoclonal [clone 4A3] (IgG2a,k) to Human TRAF3IP2 / ACT1
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
TRAF3IP2 / ACT1 Rabbit Polyclonal Unconjugated Human IHC-P, WB aa2-15 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa2-15) IHC-plus™ LS-B1429
IHC Image
IF Image
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Human
IHC - Paraffin, Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit Polyclonal Unconjugated Human IHC, WB aa554-568 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa554-568) LS-C408
IHC Image
IF Image
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Human
IHC, Western blot
Unconjugated
TRAF3IP2 / ACT1 Mouse IgG2a Monoclonal Unconjugated, Azide-free Human IHC-P, IF, WB, ELISA aa451-566 No
Anti-TRAF3IP2 / ACT1 Antibody (aa451-566, Azide-free) LS-C327076
Mouse Monoclonal (IgG2a) to Human TRAF3IP2 / ACT1
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated, Azide-free
TRAF3IP2 / ACT1 Goat Polyclonal Unconjugated Human WB, ELISA N-Terminus No Primary
Anti-TRAF3IP2 / ACT1 Antibody (N-Terminus) LS-C186619
WB Image
Goat Polyclonal to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
Unconjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal Unconjugated Human, Gorilla, Monkey, Mouse WB No Primary
Anti-TRAF3IP2 / ACT1 Antibody LS-C616
WB Image
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human, Gorilla, Monkey, Mouse
Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit Polyclonal Unconjugated Human WB aa454-483 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483) LS-C157253
WB Image
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Human
Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit Polyclonal Unconjugated Human, Rat, Pig WB N-Terminus No Primary
Anti-TRAF3IP2 / ACT1 Antibody (N-Terminus) LS-C135292
WB Image
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Human, Rat, Pig
Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit Polyclonal Unconjugated Human WB N-Terminus No Primary
Anti-TRAF3IP2 / ACT1 Antibody (N-Terminus) LS-C48309
WB Image
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Human
Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-TRAF3IP2 / ACT1 Antibody LS-C153104
Rabbit Polyclonal (IgG)
Human
Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-TRAF3IP2 / ACT1 Antibody LS-C153103
Rabbit Polyclonal (IgG)
Human
Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal Unconjugated Human, Mouse WB N-Terminus No Primary
Anti-TRAF3IP2 / ACT1 Antibody (N-Terminus) LS-C83745
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human, Mouse
Western blot
Unconjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human WB, ELISA aa454-483 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483, Azide-free, HRP) LS-C224427
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
HRP Conjugated, Azide-free
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal PE Conjugated Human WB, ELISA aa454-483 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483, PE) LS-C224432
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
PE Conjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa454-483 No
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483) LS-C325909
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
Unconjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal FITC Conjugated Human WB, ELISA aa454-483 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483, FITC) LS-C224426
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
FITC Conjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal AP Conjugated Human WB, ELISA aa454-483 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483, AP) LS-C224423
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
AP Conjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal APC Conjugated Human WB, ELISA aa454-483 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483, APC) LS-C224424
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
APC Conjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal Biotin Conjugated Human WB, ELISA aa454-483 No Primary
Anti-TRAF3IP2 / ACT1 Antibody (aa454-483, Biotin) LS-C224425
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot, ELISA
Biotin Conjugated
TRAF3IP2 / ACT1 Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-TRAF3IP2 / ACT1 Antibody LS-C309919
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
Western blot
Unconjugated

TRAF3IP2 / ACT1 Feature Table


Feature Type Location Details
alternative products 1 - 574 Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=C6ORF4; IsoId=O43734-1; Sequence=Displayed; Name=2; Synonyms=C6ORF5, C6ORF6; IsoId=O43734-2; Sequence=VSP_004163; Name=3; IsoId=O43734-3; Sequence=VSP_035733;
Function 1 - 574 Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
sequence caution 1 - 574 Sequence=BAB15507.1; Type=Erroneous initiation; Sequence=CAA15507.1; Type=Erroneous initiation;
Subunit 1 - 574 Interacts with IKBKG/NF-kappa B essential modulator, with CHUK/IKK-alpha and with IKBKB/IKK-beta.
Tissue Specificity 1 - 574 Widely expressed.
arrayexpress 1 - 574 O43734
bgee 1 - 574 O43734
cleanex 1 - 574 HS_TRAF3IP2
ctd 1 - 574 10758
doi 1 - 574 10
eggnog 1 - 574 prNOG09341
embl 1 - 574 AF136405
embl 1 - 574 AF136406
embl 1 - 574 AF136407
embl 1 - 574 AF272151
embl 1 - 574 AF274303
embl 1 - 574 AK025351
embl 1 - 574 AK026602
embl 1 - 574 AK314415
embl 1 - 574 AL008730
embl 1 - 574 AL050289
embl 1 - 574 BC002823
embl 1 - 574 CH471051
embl 1 - 574 Z97989
ensembl 1 - 574 ENST00000340026
ensembl 1 - 574 ENST00000392555
genecards 1 - 574 GC06M111877
geneid 1 - 574 10758
genevestigator 1 - 574 O43734
germonline 1 - 574 ENSG00000056972
go 1 - 574 GO:0023034
go 1 - 574 GO:0043123
hgnc 1 - 574 HGNC:1343
hovergen 1 - 574 HBG002060
inparanoid 1 - 574 O43734
intact 1 - 574 O43734
interpro 1 - 574 IPR013568
ipi 1 - 574 IPI00013883
ipi 1 - 574 IPI00170492
ipi 1 - 574 IPI00478211
kegg 1 - 574 hsa:10758
medline 1 - 574 20363742
medline 1 - 574 20442402
medline 1 - 574 20442403
medline 1 - 574 22935763
mim 1 - 574 607043
mint 1 - 574 MINT-143208
nextbio 1 - 574 40857
pfam 1 - 574 PF08357
pharmgkb 1 - 574 PA25938
pir 1 - 574 T08794
pride 1 - 574 O43734
proteinmodelportal 1 - 574 O43734
pubmed 1 - 574 10903453
pubmed 1 - 574 10962024
pubmed 1 - 574 10962033
pubmed 1 - 574 14574404
pubmed 1 - 574 14702039
pubmed 1 - 574 15489334
pubmed 1 - 574 17974005
refseq 1 - 574 NP_001157753.1
refseq 1 - 574 NP_001157754.1
refseq 1 - 574 NP_001157755.1
refseq 1 - 574 NP_679211.2
string 1 - 574 O43734
ucsc 1 - 574 uc003pve.1
unigene 1 - 574 Hs.561514
alt_init; genomic_dna 1 - 574 CAA15507.1
alt_init; mrna 1 - 574 BAB15507.1
joined; genomic_dna 1 - 574 CAI22298.1
chain 1 - 574 Adapter protein CIKS /FTId=PRO_0000089751.
conflict 334 - 334 E -> D (in Ref. 3; AAG15407)
conflict 347 - 347 P -> S (in Ref. 1; AAF67447)
conflict 463 - 463 Missing (in Ref. 4; BAB15117)
var_seq 1 - 9 Missing (in isoform 2) /FTId=VSP_004163.
var_seq 1 - 421 Missing (in isoform 3) /FTId=VSP_035733.
variant 19 - 19 D -> N (in dbSNP:rs33980500) /FTId=VAR_047349.
variant 83 - 83 R -> W (in dbSNP:rs13190932) /FTId=VAR_031227.
variant 332 - 332 Q -> H (in dbSNP:rs1043730) /FTId=VAR_024307.
keyword 1 - 574 Alternative splicing
keyword 1 - 574 Complete proteome
keyword 1 - 574 Polymorphism
Molecular Weight 1 - 574 64657
1 hit 1 - 574 PF08357

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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