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Unfortunately, the antibody LS-C187791 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TGFB1 / TGF Beta 1 Antibodies

transforming growth factor, beta 1

TGF Beta is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. It plays an important role in bone remodeling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation, and differentiation in committed osteoblasts.

Gene Name: transforming growth factor, beta 1
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: TGFB1 Antibody, CED Antibody, DPD1 Antibody, Diaphyseal dysplasia 1 Antibody, LAP Antibody, Latency-associated peptide Antibody, TGF Beta Antibody, TGFbeta Antibody, TGF-beta 1 protein Antibody, TGF-beta-1 Antibody, TGFB Antibody
Target Sequences: NM_000660 NP_000651.3 P01137
 TGFB1 / TGF Beta 1 Feature Table
Featured Image

Featured TGFB1 / TGF Beta 1 Antibody

LS-B655 is a rabbit polyclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.


TGFB1 / TGF Beta 1 Antibodies (59)

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human IHC-P, IF, WB, ELISA aa286-293 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa286-293) IHC-plus™ LS-B655
IHC Image
WB Image
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC-P, WB, ELISA aa336-385 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa336-385) IHC-plus™ LS-B5663
IHC Image
WB Image
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal TB 21 Unconjugated Human, Rat, Sheep, Mustelid IHC-P, IHC-Fr, Flo, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone TB 21) IHC-plus™ LS-B9464
IHC Image
Mouse Monoclonal [clone TB 21] (IgG1) to Human TGFB1 / TGF Beta 1
Human, Rat, Sheep, Mustelid
IHC - Paraffin, IHC - Frozen, Flow Cytometry, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Mouse, Human, Bovine, Dog, Guinea pig, Horse, Sheep IHC-P, WB aa191-240 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa191-240) IHC-plus™ LS-B4577
IHC Image
WB Image
Rabbit Polyclonal (IgG) to Mouse TGFB1 / TGF Beta 1
Mouse, Human, Bovine, Dog, Guinea pig, Horse, Sheep
IHC - Paraffin, Western blot
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal Unconjugated Human IHC-P, WB, ELISA, Neut No Primary
Anti-TGFB1 / TGF Beta 1 Antibody IHC-plus™ LS-B9832
IHC Image
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
IHC - Paraffin, Western blot, ELISA, Neutralization
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal 2AR2 Unconjugated Human, Mouse, Rat IHC, WB, Flo, ELISA, Neut No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone 2AR2) LS-C10854
Mouse Monoclonal [clone 2AR2] (IgG1) to Human TGFB1 / TGF Beta 1
Human, Mouse, Rat
IHC, Western blot, Flow Cytometry, ELISA, Neutralization
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human, Mouse IHC-P, IF, WB aa29-58 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa29-58) LS-C161825
IHC Image
IF Image
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C136912
IHC Image
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human, Mouse, Rat
IHC, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Chicken IgY Polyclonal Biotin Conjugated Human, Mouse WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (Biotin) LS-C10856
Chicken Polyclonal (IgY) to Human TGFB1 / TGF Beta 1
Human, Mouse
Western blot, ELISA
Biotin Conjugated
TGFB1 / TGF Beta 1 Goat IgG Polyclonal Unconjugated Human IHC, ICC, WB, Flo, ELISA, Neut No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C195777
Goat Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
IHC, ICC, Western blot, Flow Cytometry, ELISA, Neutralization
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal 2AR2 Biotin Conjugated Human, Mouse, Rat IHC, WB, Flo, ELISA, Neut No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone 2AR2, Biotin) LS-C10855
Mouse Monoclonal [clone 2AR2] (IgG1) to Human TGFB1 / TGF Beta 1
Human, Mouse, Rat
IHC, Western blot, Flow Cytometry, ELISA, Neutralization
Biotin Conjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Pig, Mouse, Rat IHC, WB aa280-391 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa280-391) LS-C10857
Rabbit Polyclonal to Pig TGFB1 / TGF Beta 1
Pig, Mouse, Rat
IHC, Western blot
Unconjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Mouse, Human, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep WB aa151-200 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa151-200) LS-C80166
WB Image
Rabbit Polyclonal (IgG) to Mouse TGFB1 / TGF Beta 1
Mouse, Human, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep
Western blot
Unconjugated
TGFB1 / TGF Beta 1 Rat IgG2a,k Monoclonal TB2F Unconjugated Human ELISA, SwELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone TB2F) LS-C107415
Rat Monoclonal [clone TB2F] (IgG2a,k) to Human TGFB1 / TGF Beta 1
Human
ELISA, Sandwich ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal Unconjugated Human IHC, WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C104537
IHC Image
IHC Image
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
IHC, Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal 7F6 Unconjugated Human IHC, WB, Flo, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone 7F6) LS-C169097
IHC Image
IHC Image
Mouse Monoclonal [clone 7F6] (IgG1) to Human TGFB1 / TGF Beta 1
Human
IHC, Western blot, Flow Cytometry, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C136911
IHC Image
IHC Image
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB Tyr369 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (Tyr369) LS-C176242
IHC Image
WB Image
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG2a Monoclonal Unconjugated Human IHC-P, WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C41424
WB Image
Mouse Monoclonal (IgG2a) to Human TGFB1 / TGF Beta 1
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat, Pig IHC, WB No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C48916
WB Image
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human, Mouse, Rat, Pig
IHC, Western blot
Unconjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal FITC Conjugated Human IHC, WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (FITC) LS-C212029
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
IHC, Western blot, ELISA
FITC Conjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Biotin Conjugated Human IHC, WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (Biotin) LS-C212031
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
IHC, Western blot, ELISA
Biotin Conjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Human IHC, WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C212026
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
IHC, Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal HRP Conjugated Human IHC, WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (HRP) LS-C212027
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
IHC, Western blot, ELISA
HRP Conjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Pig, Mouse, Rat IHC, WB No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C194988
Rabbit Polyclonal to Pig TGFB1 / TGF Beta 1
Pig, Mouse, Rat
IHC, Western blot
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal Unconjugated Human IHC, WB, ELISA, Func, Neut No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C18192
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
IHC, Western blot, ELISA, Functional Assay, Neutralization
Unconjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal AP Conjugated Human, Mouse IHC, ICC, WB, ELISA aa29-58 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa29-58, AP) LS-C271376
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human, Mouse
IHC, ICC, Western blot, ELISA
AP Conjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal APC Conjugated Human, Mouse IHC, ICC, WB, ELISA aa29-58 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa29-58, APC) LS-C271375
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human, Mouse
IHC, ICC, Western blot, ELISA
APC Conjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal PE Conjugated Human, Mouse IHC, ICC, WB, ELISA aa29-58 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa29-58, PE) LS-C271374
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human, Mouse
IHC, ICC, Western blot, ELISA
PE Conjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Pig, Human, Mouse, Rat IHC, WB No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C10852
Rabbit Polyclonal (IgG) to Pig TGFB1 / TGF Beta 1
Pig, Human, Mouse, Rat
IHC, Western blot
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal Unconjugated Human WB, ELISA aa1-111 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa1-111) LS-C137614
WB Image
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG2a Monoclonal 4F9C10 Unconjugated Human WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone 4F9C10) LS-C82186
WB Image
Mouse Monoclonal [clone 4F9C10] (IgG2a) to Human TGFB1 / TGF Beta 1
Human
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human ICC pTyr369 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (phospho-Tyr369) LS-C180170
ICC Image
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
ICC
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG2a Monoclonal 3B6 Unconjugated Human WB No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone 3B6) LS-C174800
WB Image
Mouse Monoclonal [clone 3B6] (IgG2a) to Human TGFB1 / TGF Beta 1
Human
Western blot
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal M66 Unconjugated Human WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone M66) LS-C85455
Mouse Monoclonal [clone M66] (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal 16TFB Biotin Conjugated Human ELISA, SwELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone 16TFB, Biotin) LS-C106686
Mouse Monoclonal [clone 16TFB] (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
ELISA, Sandwich ELISA
Biotin Conjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Zebrafish WB, ELISA Internal No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (Internal) LS-C209826
Rabbit Polyclonal (IgG) to Zebrafish TGFB1 / TGF Beta 1
Zebrafish
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal DY488 Conjugated Human ICC pTyr369 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (phospho-Tyr369, DY488) LS-C180884
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
ICC
DY488 Conjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal DY550 Conjugated Human ICC pTyr369 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (phospho-Tyr369, DY550) LS-C180885
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
ICC
DY550 Conjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal DY650 Conjugated Human ICC pTyr369 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (phospho-Tyr369, DY650) LS-C180883
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
ICC
DY650 Conjugated
TGFB1 / TGF Beta 1 Mouse IgG Monoclonal 3F12 Unconjugated Human ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (clone 3F12) LS-C198337
Mouse Monoclonal [clone 3F12] (IgG) to Human TGFB1 / TGF Beta 1
Human
ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Biotin Conjugated Human ICC pTyr369 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (phospho-Tyr369, Biotin) LS-C180882
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
ICC
Biotin Conjugated
TGFB1 / TGF Beta 1 Chicken Polyclonal Unconjugated Human No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C196534
Chicken Polyclonal to Human TGFB1 / TGF Beta 1
Human
Unconjugated
TGFB1 / TGF Beta 1 Goat IgG Polyclonal Unconjugated Human ELISA, Neut No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C18187
Goat Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
ELISA, Neutralization
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal Unconjugated Human WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C18189
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal Unconjugated Human WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C18191
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Zebrafish, Fish WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C182501
Rabbit Polyclonal (IgG) to Zebrafish TGFB1 / TGF Beta 1
Zebrafish, Fish
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal Unconjugated Human WB, ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C10858
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Rabbit Polyclonal Unconjugated Human WB, ELISA aa286-293 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa286-293) LS-C10859
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
Western blot, ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal APC Conjugated Human Flo aa30-390 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa30-390, APC) LS-C132628
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Flow Cytometry
APC Conjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal APC Conjugated Human Flo No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (APC) LS-C132627
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Flow Cytometry
APC Conjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal CF Conjugated Human Flo aa30-390 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa30-390, CF) LS-C132629
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Flow Cytometry
CF Conjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal APC Conjugated Human, Mouse Flo aa30-278 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa30-278, APC) LS-C132631
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human, Mouse
Flow Cytometry
APC Conjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal PerCP Conjugated Human, Mouse Flo aa30-278 No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (aa30-278, PerCP) LS-C132630
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human, Mouse
Flow Cytometry
PerCP Conjugated
TGFB1 / TGF Beta 1 Rabbit IgG Polyclonal Unconjugated Human, Rat WB N-Terminus No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (N-Terminus) LS-C26376
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human, Rat
Western blot
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal Unconjugated Human ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C18193
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal PE Conjugated Human Flo No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (PE) LS-C37155
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Flow Cytometry
PE Conjugated
TGFB1 / TGF Beta 1 Mouse IgG1,k Monoclonal Unconjugated Human ELISA No Primary
Anti-TGFB1 / TGF Beta 1 Antibody LS-C39830
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
ELISA
Unconjugated
TGFB1 / TGF Beta 1 Mouse IgG1 Monoclonal PE Conjugated Human Flo No Primary
Anti-TGFB1 / TGF Beta 1 Antibody (PE) LS-C39827
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Flow Cytometry
PE Conjugated

TGFB1 / TGF Beta 1 Feature Table


Feature Type Location Details
Disease 1 - 390 Defects in TGFB1 are the cause of Camurati-Engelmann disease (CED) [MIM:131300]; also known as progressive diaphyseal dysplasia 1 (DPD1). CED is an autosomal dominant disorder characterized by hyperostosis and sclerosis of the diaphyses of long bones. The disease typically presents in early childhood with pain, muscular weakness and waddling gait, and in some cases other features such as exophthalmos, facial paralysis, hearing difficulties and loss of vision.
Function 1 - 390 Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Induction 1 - 390 Activated in vitro at pH below 3.5 and over 12.5.
interaction 1 - 390 P05067:APP; NbExp=1; IntAct=EBI-779636, EBI-77613;
polymorphism 1 - 390 In post-menopausal Japanese women, the frequency of Leu-10 is higher in subjects with osteoporosis than in controls.
ptm 1 - 390 Glycosylated.
ptm 1 - 390 The precursor is cleaved into mature TGF-beta-1 and LAP, which remains non-covalently linked to mature TGF-beta-1 rendering it inactive.
Similarity 1 - 390 Belongs to the TGF-beta family.
Subcellular Location 1 - 390 Secreted, extracellular space, extracellular matrix.
Subunit 1 - 390 The inactive form consists of a TGFB1 homodimer non- covalently linked to a latency-associated peptide (LAP) homodimer. The inactive complex can contain a latent TGFB1-binding protein. The active form is a homodimer of mature TGFB1; disulfide-linked. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN.
Tissue Specificity 1 - 390 Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage.
web resource 1 - 390 Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/TGFB1";
web resource 1 - 390 Name=Wikipedia; Note=TGF beta-1 entry; URL="http://en.wikipedia.org/wiki/TGF_beta_1";
arrayexpress 1 - 390 P01137
bgee 1 - 390 P01137
cleanex 1 - 390 HS_TGFB1
ctd 1 - 390 7040
dip 1 - 390 DIP-5934N
doi 1 - 390 10
drugbank 1 - 390 DB00070
eggnog 1 - 390 prNOG16068
embl 1 - 390 AK291907
embl 1 - 390 BC000125
embl 1 - 390 BC001180
embl 1 - 390 BC022242
embl 1 - 390 BT007245
embl 1 - 390 CH471126
embl 1 - 390 M38449
embl 1 - 390 X02812
embl 1 - 390 X05839
embl 1 - 390 X05840
embl 1 - 390 X05843
embl 1 - 390 X05844
embl 1 - 390 X05849
embl 1 - 390 X05850
ensembl 1 - 390 ENST00000221930
genecards 1 - 390 GC19M041837
geneid 1 - 390 7040
genevestigator 1 - 390 P01137
germonline 1 - 390 ENSG00000105329
go 1 - 390 GO:0001933
go 1 - 390 GO:0002062
go 1 - 390 GO:0002244
go 1 - 390 GO:0002248
go 1 - 390 GO:0005114
go 1 - 390 GO:0005578
go 1 - 390 GO:0005634
go 1 - 390 GO:0005796
go 1 - 390 GO:0006611
go 1 - 390 GO:0006754
go 1 - 390 GO:0006917
go 1 - 390 GO:0007050
go 1 - 390 GO:0007173
go 1 - 390 GO:0007179
go 1 - 390 GO:0007183
go 1 - 390 GO:0007184
go 1 - 390 GO:0007435
go 1 - 390 GO:0008083
go 1 - 390 GO:0008156
go 1 - 390 GO:0010718
go 1 - 390 GO:0010742
go 1 - 390 GO:0010763
go 1 - 390 GO:0010800
go 1 - 390 GO:0010862
go 1 - 390 GO:0016049
go 1 - 390 GO:0016202
go 1 - 390 GO:0016563
go 1 - 390 GO:0017015
go 1 - 390 GO:0019049
go 1 - 390 GO:0022408
go 1 - 390 GO:0030308
go 1 - 390 GO:0030501
go 1 - 390 GO:0031093
go 1 - 390 GO:0031575
go 1 - 390 GO:0032355
go 1 - 390 GO:0032570
go 1 - 390 GO:0032740
go 1 - 390 GO:0032801
go 1 - 390 GO:0032967
go 1 - 390 GO:0033138
go 1 - 390 GO:0035307
go 1 - 390 GO:0043406
go 1 - 390 GO:0043536
go 1 - 390 GO:0043537
go 1 - 390 GO:0043552
go 1 - 390 GO:0043932
go 1 - 390 GO:0045216
go 1 - 390 GO:0045599
go 1 - 390 GO:0045930
go 1 - 390 GO:0048298
go 1 - 390 GO:0048535
go 1 - 390 GO:0050680
go 1 - 390 GO:0050714
go 1 - 390 GO:0050921
go 1 - 390 GO:0051781
go 1 - 390 GO:0051897
go 1 - 390 GO:0060389
go 1 - 390 GO:0060391
go 1 - 390 GO:0070723
h-invdb 1 - 390 HIX0015152
hgnc 1 - 390 HGNC:11766
hogenom 1 - 390 HBG444250
hovergen 1 - 390 HBG074115
hpa 1 - 390 CAB000361
inparanoid 1 - 390 P01137
intact 1 - 390 P01137
interpro 1 - 390 IPR001111
interpro 1 - 390 IPR001839
interpro 1 - 390 IPR003939
interpro 1 - 390 IPR015615
interpro 1 - 390 IPR016319
interpro 1 - 390 IPR017948
ipi 1 - 390 IPI00000075
kegg 1 - 390 hsa:7040
medline 1 - 390 20428174
medline 1 - 390 20517332
medline 1 - 390 21611382
medline 1 - 390 22191656
medline 1 - 390 22486658
medline 1 - 390 22726942
medline 1 - 390 85131019
medline 1 - 390 85296301
medline 1 - 390 87174845
medline 1 - 390 88198190
medline 1 - 390 93144319
medline 1 - 390 93144320
medline 1 - 390 93229900
medline 1 - 390 96266150
medline 1 - 390 97294774
medline 1 - 390 98454866
mim 1 - 390 131300
mim 1 - 390 190180
nextbio 1 - 390 27507
ogp 1 - 390 P01137
orphanet 1 - 390 1328
orphanet 1 - 390 98963
panther 1 - 390 PTHR11848
pathway_interaction_db 1 - 390 glypican_1pathway
pathway_interaction_db 1 - 390 il12_stat4pathway
pathway_interaction_db 1 - 390 il27pathway
pathway_interaction_db 1 - 390 rxr_vdr_pathway
pathway_interaction_db 1 - 390 syndecan_2_pathway
pathway_interaction_db 1 - 390 tgfbrpathway
pdb 1 - 390 1KLA
pdb 1 - 390 1KLC
pdb 1 - 390 1KLD
pdb 1 - 390 3KFD
pdbsum 1 - 390 1KLA
pdbsum 1 - 390 1KLC
pdbsum 1 - 390 1KLD
pdbsum 1 - 390 3KFD
pfam 1 - 390 PF00019
pfam 1 - 390 PF00688
pharmgkb 1 - 390 PA350
pir 1 - 390 A27513
pirsf 1 - 390 PIRSF001787
pride 1 - 390 P01137
prints 1 - 390 PR01423
prints 1 - 390 PR01424
prosite 1 - 390 PS00250
prosite 1 - 390 PS51362
proteinmodelportal 1 - 390 P01137
pubmed 1 - 390 10973241
pubmed 1 - 390 11062463
pubmed 1 - 390 11746498
pubmed 1 - 390 12202987
pubmed 1 - 390 12493741
pubmed 1 - 390 12843182
pubmed 1 - 390 14702039
pubmed 1 - 390 15489334
pubmed 1 - 390 16263699
pubmed 1 - 390 16335952
pubmed 1 - 390 16754747
pubmed 1 - 390 17827158
pubmed 1 - 390 2982829
pubmed 1 - 390 3162913
pubmed 1 - 390 3470709
pubmed 1 - 390 3861940
pubmed 1 - 390 8424942
pubmed 1 - 390 8424943
pubmed 1 - 390 8471846
pubmed 1 - 390 8679613
pubmed 1 - 390 9150447
pubmed 1 - 390 9783545
pubmed 1 - 390 9895299
reactome 1 - 390 REACT_604
reactome 1 - 390 REACT_6167
reactome 1 - 390 REACT_6844
refseq 1 - 390 NP_000651.3
smart 1 - 390 SM00204
string 1 - 390 P01137
unigene 1 - 390 Hs.645227
alt_seq; mrna 1 - 390 CAA26580.1
joined; genomic_dna 1 - 390 CAA29283.1
carbohyd 82 - 82 N-linked (GlcNAc...)
carbohyd 136 - 136 N-linked (GlcNAc...) (By similarity)
carbohyd 176 - 176 N-linked (GlcNAc...) (By similarity)
chain 30 - 278 Latency-associated peptide /FTId=PRO_0000033762.
chain 279 - 390 Transforming growth factor beta-1 /FTId=PRO_0000033763.
conflict 159 - 159 R -> RR (in Ref. 2; CAA26580)
disulfid 355 - 355 Interchain
motif 244 - 246 Cell attachment site (Potential)
variant 10 - 10 L -> P (associated with higher bone mineral density and lower frequency of vertebral fractures in Japanese post- menopausal women; dbSNP:rs1800470). /FTId=VAR_016171.
variant 25 - 25 R -> P (in dbSNP:rs1800471) /FTId=VAR_016172.
variant 81 - 81 Y -> H (in CED; leads to TGF-beta-1 intracellular accumulation). /FTId=VAR_017607.
variant 218 - 218 R -> C (in CED; higher levels of active TGF-beta-1 in the culture medium; enhances osteoclast formation in vitro). /FTId=VAR_017608.
variant 218 - 218 R -> H (in CED) /FTId=VAR_017609.
variant 222 - 222 H -> D (in CED; sporadic case; higher levels of active TGF-beta-1 in the culture medium). /FTId=VAR_017610.
variant 225 - 225 C -> R (in CED; higher levels of active TGF-beta-1 in the culture medium). /FTId=VAR_017611.
variant 263 - 263 T -> I (in dbSNP:rs1800472) /FTId=VAR_016173.
keyword 1 - 390 3D-structure
keyword 1 - 390 Cleavage on pair of basic residues
keyword 1 - 390 Complete proteome
keyword 1 - 390 Direct protein sequencing
keyword 1 - 390 Disease mutation
keyword 1 - 390 Disulfide bond
keyword 1 - 390 Extracellular matrix
keyword 1 - 390 Glycoprotein
keyword 1 - 390 Growth factor
keyword 1 - 390 Mitogen
keyword 1 - 390 Polymorphism
keyword 1 - 390 Secreted
keyword 1 - 390 Signal
Molecular Weight 1 - 390 44341
1 hit 1 - 390 PF00019
1 hit 1 - 390 PF00688
1 hit 1 - 390 PS00250
1 hit 1 - 390 PS51362

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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