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TBX1

T-box 1

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: T-box 1
Synonyms: TBX1, DGCR, DORV, DGS, T-box 1, T-box 1 transcription factor C, TBX1C, TGA, CAFS, CTHM, T-box protein 1, Testis-specific T-box protein, VCFS
Target Sequences: NM_005992 NP_005983.1 O43435

Publications (3)

1
Rebalancing gene haploinsufficiency in vivo by targeting chromatin. Fulcoli FG, Franzese M, Liu X, Zhang Z, Angelini C, Baldini A. Nature communications. 2016 7:11688. (ChIP-Seq; Mouse) [Full Text Article] [PubMed:27256596] [PMC:PMC4895808] Related Antibodies: LS-C31179.
2
Cardiopharyngeal mesoderm origins of musculoskeletal and connective tissues in the mammalian pharynx. Noritaka Adachi, Marchesa Bilio, Antonio Baldini, Robert G Kelly. Development (Cambridge, England). 2020 February;147: [Full Text Article] [PubMed:32014863] Related Antibodies: LS-C31179.
3
Generation of an induced pluripotent stem cell line carrying a biallelic deletion (SCTCi019-A) in GCDH using CRISPR/Cas9. Imke M E Schuurmans, Ka M Wu, Clara D M van Karnebeek, Nael Nadif Kasri, Alejandro Garanto. Stem cell research. 2023 June;69:103069. [Full Text Article] [PubMed:36947993] Related Antibodies: LS-C416020.

☰ Filters
Products
Antibodies (41)
Primary (41)
TBX1 (41)
Human (35)
Mouse (13)
Rat (6)
Dog (3)
Gibbon (6)
Guinea pig (6)
Rabbit (6)
IHC (18)
IHC-Fr (1)
IHC-P (9)
WB (36)
ELISA (10)
ICC (7)
IF (14)
IP (6)
Peptide-ELISA (3)
rabbit (39)
mouse (2)
Product Group
IHCPlus (2)
IgG (30)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (38)
recombinant monoclonal rmc (1)
OTI1C2 (2)
RBT-TBXT (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Ready-to-Use (1)
Unconjugated (19)
aa327-356 (7)
Internal (5)
aa324-373 (4)
aa396-445 (4)
280-360 aa, C-terminal (1)
C-Terminus (1)
Lys347 (1)
aa298-347 (1)
aa311-360 (1)
No (39)
Yes (2)
TBX1 Antibody - TBX1 antibody ARP33399_T100-NP_542378-TBX1 (T-box 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TBX1 Rabbit anti-Human Polyclonal (aa396-445) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
TBX1 Antibody - TBX1 antibody ARP33399_T100-NP_542378-TBX1 (T-box 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TBX1 Rabbit anti-Human Polyclonal (aa396-445) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Gibbon, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
TBX1 Antibody - TBX1 antibody ARP33399_T100-NP_542378-TBX1 (T-box 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TBX1 Rabbit anti-Human Polyclonal (aa396-445) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Gibbon, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
TBX1 Antibody - TBX1 antibody ARP33399_T100-NP_542378-TBX1 (T-box 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TBX1 Rabbit anti-Human Polyclonal (aa396-445) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Gibbon, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
TBX1 Antibody - Anti-TBX1 / Brachyury antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.
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TBX1 Rabbit anti-Human Polyclonal (aa327-356) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
TBX1 Antibody - Western blot of TBX1 (K347) pAb in extracts from COLO 205 cells.
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TBX1 Rabbit anti-Human Polyclonal (Lys347) Antibody
Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
TBX1 Antibody - Western blot of COLO205 cell lysate using TBX1 Antibody
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TBX1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
TBX1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TBX1 Rabbit anti-Mouse Polyclonal (Internal) Antibody
Mouse
IHC, IHC-P, IP, WB
Unconjugated
50 µg/$485
TBX1 Antibody - Immunohistochemical analysis of TBX1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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TBX1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
TBX1 Antibody - Lane: Fetal Lung Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TBX1 Rabbit anti-Human Polyclonal (aa324-373) Antibody
Human
WB
Unconjugated
100 µl/$424
TBX1 Antibody - Lane: Fetal Lung Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TBX1 Rabbit anti-Human Polyclonal (aa324-373) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Rat, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
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TBX1 Rabbit anti-Human Polyclonal (aa327-356) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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TBX1 Rabbit anti-Human Polyclonal (aa327-356) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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TBX1 Rabbit anti-Human Polyclonal (aa327-356) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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TBX1 Rabbit anti-Human Polyclonal (aa327-356) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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TBX1 Rabbit anti-Human Polyclonal (aa327-356) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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TBX1 Rabbit anti-Human Polyclonal (aa327-356) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
TBX1 Antibody - Western blot of TBX1 antibody
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TBX1 Rabbit anti-Human Polyclonal (280-360 aa, C-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TBX1 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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TBX1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TBX1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using TBX1 Polyclonal Antibody at dilution of 1:40(×200)
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TBX1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TBX1 Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-TBX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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TBX1 Mouse anti-Human Monoclonal (OTI1C2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TBX1 Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-TBX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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TBX1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TBX1 Antibody - Immunofluorescence analysis of A549 cells, using TBX1 Antibody. The picture on the right is blocked with the synthesized peptide.
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TBX1 Rabbit anti-Human Polyclonal (aa311-360) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TBX1 Antibody - Immunofluorescent analysis of PC3 cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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TBX1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
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TBX1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 41 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).