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SOX9

SRY (sex determining region Y)-box 9

The SOX9 protein recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Gene Name: SRY (sex determining region Y)-box 9
Family/Subfamily: Transcription factor
Synonyms: SOX9, CMD1, CMPD1, SRY-related HMG-box, gene 9, Transcription factor SOX-9
Target Sequences: NM_000346 NP_000337.1 P48436

Publications (3)

1
The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. Malhotra GK, Zhao X, Edwards E, Kopp JL, Naramura M, Sander M, Band H, Band V. BMC developmental biology. 2014 14:47. (WB; Mouse) [Full Text Article] [PubMed:25527186] [PMC:PMC4297388] Related Antibodies: LS-B5761.
2
Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs. Lyess Allas, Quitterie Rochoux, Sylvain Leclercq, Karim Boumédiene, Catherine Baugé. Laboratory investigation; a journal of technical methods and pathology. 2020 January;100:64-71. [Full Text Article] [PubMed:31409892] Related Antibodies: LS-C368527.
3
Specific inhibition of FAK signaling attenuates subchondral bone deterioration and articular cartilage degeneration during osteoarthritis pathogenesis. Hangtian Wu, Ting Xu, Zhigang Chen, Yutian Wang, Kaiqun Li, Pei-Sheng Chen, Zilong Yao, Jianwen Su, Caiyu Cheng, Xiaohu Wu, Hongan Zhang, Yu Chai, Xianrong Zhang, Yanjun Hu, Bin Yu, Zhuang Cui. Journal of cellular physiology. 2020 November;235:8653-8666. [Full Text Article] [PubMed:32324278] Related Antibodies: LS-C368527.

☰ Filters
Products
Proteins (7)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (2)
Recombinant (4)
SOX9 (7)
No (7)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
Supernatant (1)
Low endotoxin level (1)
SOX9 Protein - Purified recombinant protein SOX9 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
56 kDa
20 µg/$1,107
SOX9 Protein - 12.5% SDS-PAGE of human SOX9 stained with Coomassie Blue
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Wheat Germ Extract
GST
82.5 kDa
10 µg/$479; 25 µg/$670
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E. coli
89 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
9.9 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
SOX9 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
HEK 293 Cells
His, N-Terminal
~56 kDa
200 µl/$283
SOX9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
56 kDa
20 µg/$150
SOX9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).