RSPO4

R-spondin 4

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway.

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Products

ELISA Kits (3)

Type

Sandwich (3)

Target

RSPO4 (3)

Reactivity

Human (2)

Mouse (1)

Format

96-Well Strip Plate (3)

Publications

No (3)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (1)

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Human RSPO4 (Sandwich ELISA) ELISA Kit - LS-F31683

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$632

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Human RSPO4 (Sandwich ELISA) ELISA Kit - LS-F39992

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$901

Select

Mouse RSPO4 (Sandwich ELISA) ELISA Kit - LS-F54665

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

34.4 - 2200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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