RAD51L3 / RAD51D

RAD51 paralog D

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

RAD51L3 / RAD51D (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His (2)

Myc-DDK (Flag) (4)

Species

Human (6)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human RAD51L3 / RAD51D Protein (Recombinant His) - LS-G2758

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Human RAD51L3 / RAD51D Protein (Recombinant GST, N-terminus) (aa1-328) - LS-G64219

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human RAD51L3 / RAD51D Protein (Recombinant GST) (Full Length) - LS-G30096

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.82 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RAD51L3 / RAD51D Protein (Recombinant His) - LS-G2722

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human RAD51L3 / RAD51D Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80462

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.8 kDa

Price:

20 µg/$150

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Human RAD51L3 / RAD51D Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80463

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

20 µg/$150

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RAD51L3 / RAD51D Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117702

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

100 µg/$494

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RAD51L3 / RAD51D Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126018

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.8 kDa

Price:

100 µg/$494

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