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PTGS1 / COX-1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Gene Name: prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms: PTGS1, COX1, Cyclooxygenase-1, COX-1, PES-1, PGH synthase 1, Prostaglandin G/H synthase 1, PTGHS, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS 1, PHS1, Prostaglandin H2 synthase 1
Target Sequences: NM_000962 NP_000953.2 P23219

Publications (1)

1
Inhibition of Pro-inflammatory and Anti-apoptotic Biomarkers during Experimental Oral Cancer Chemoprevention by Dietary Black Raspberries. Oghumu S, Casto BC, Ahn-Jarvis J, Weghorst LC, Maloney J, Geuy P, Horvath KZ, Bollinger CE, Warner BM, Summersgill KF, Weghorst CM, Knobloch TJ. Frontiers in immunology. 2017 October;8:1325. [Full Text Article] [PubMed:29109723] [PMC:PMC5660285]

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Products
ELISA Kits (23)
Cell-Based (1)
Competitive EIA (1)
Sandwich (19)
Sandwich CLIA (2)
PTGS1 / COX-1 (23)
Human (7)
Mouse (3)
Rat (6)
Bovine (1)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (4)
96-Well Strip Plate (18)
No (22)
Yes (1)
Adherent Cell Cultures (1)
Plasma (18)
Serum (18)
Tissue Homogenates (8)
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$771
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PTGS1 / COX-1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Bovine
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PTGS1 / COX-1 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PTGS1 / COX-1 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,041
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
PTGS1 / COX-1 ELISA Kit
Select
Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Viewing 1-23 of 23 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).