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POU2F3 / PLA-1

POU class 2 homeobox 3

POU2F3 / PLA-1 is a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: POU class 2 homeobox 3
Synonyms: POU2F3, Epoc-1, Octamer-binding protein 11, POU class 2 homeobox 3, Transcription factor PLA-1, Transcription factor Skn-1, PLA-1, PLA1, OCT-11, OCT11, OTF-11, OTF11, Skn-1a
Target Sequences: NM_014352 NP_055167.2 Q9UKI9

Publications (1)

1
Integrated Immunohistochemical Study on Small-Cell Carcinoma of the Lung Focusing on Transcription and Co-Transcription Factors. Younosuke Sato, Isamu Okamoto, Hiroki Kameyama, Shinji Kudoh, Haruki Saito, Mune Sanada, Noritaka Kudo, Joeji Wakimoto, Kosuke Fujino, Yuki Ikematsu, Kentaro Tanaka, Ayako Nishikawa, Ryo Sakaguchi, Takaaki Ito. Diagnostics (Basel, Switzerland). 2020 November;10: [Full Text Article] [PubMed:33202998] [PMC:PMC7697657] Related Antibodies: LS-B12579.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
POU2F3 / PLA-1 (5)
No (5)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Low endotoxin level (1)
POU2F3 / PLA-1 Protein - Purified recombinant protein POU2F3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
47.3 kDa
20 µg/$1,107
POU2F3 / PLA-1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
199 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
22 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
POU2F3 / PLA-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
47.3 kDa
20 µg/$150
POU2F3 / PLA-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.3 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).