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Unfortunately, the antibody LS-C191201 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PMP22 Antibodies

peripheral myelin protein 22

PMP22 is a major component of myelin expressed in the compact portion of essentially all myelinated fibers in the peripheral nervous system and is produced predominantly by Schwann cells. Studies in injured nerve suggested a role during Schwann cell growth and differentiation. PMP22 is expressed in cranial nerves but not in the mature central nervous system. Studies suggest a possible role of the PMP22 gene in the development of neoplasia in patients with neurofibromatosis and in the myelin degenerative Charcot-Marie-Tooth disease linked to chromosome 17p.

Gene Name: peripheral myelin protein 22
Synonyms: PMP22 Antibody, CMT1E Antibody, DSS Antibody, GAS-3 Antibody, GAS3 Antibody, Growth arrest-specific 3 Antibody, HMSNIA Antibody, PMP-22 Antibody, CMT1A Antibody, HNPP Antibody, Peripheral myelin protein 22 Antibody
Target Sequences: NM_000304 NP_000295.1 Q01453
 PMP22 Feature Table
Featured Image

Featured PMP22 Antibody

LS-B1294 is a rabbit polyclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.

Publications (1)

1
Characterization of a monoclonal antibody specific for human peripheral myelin protein 22 and its use in immunohistochemical studies of the fetal and adult nervous system. Gregson NA, Zhang G, Pritchard J, Wang A, Sanvito L, Hayday AC, Hughes RA. Journal of the peripheral nervous system : JPNS. 2007 12:10-Feb. (IHC) [PubMed:17374097] Related Antibodies: LS-C33995.

PMP22 Antibodies (29)

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
PMP22 Rabbit Polyclonal Unconjugated Human IHC-P C-Terminus No Primary
Anti-PMP22 Antibody (C-Terminus) IHC-plus™ LS-B1294
IHC Image
Rabbit Polyclonal to Human PMP22
Human
IHC - Paraffin
Unconjugated
PMP22 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC, WB Ala142 No Primary
Anti-PMP22 Antibody (Ala142) LS-C176553
IHC Image
WB Image
Rabbit Polyclonal to Human PMP22
Human, Mouse, Rat
IHC, Western blot
Unconjugated
PMP22 Mouse IgG1 Monoclonal CF1 Unconjugated Human, Monkey IHC-P, WB Extracellular Domain No Primary
Anti-PMP22 Antibody (Extracellular Domain, clone CF1) LS-C140125
IHC Image
Mouse Monoclonal [clone CF1] (IgG1) to Human PMP22
Human, Monkey
IHC - Paraffin, Western blot
Unconjugated
PMP22 Rabbit Polyclonal Unconjugated Human IHC C-Terminus No Primary
Anti-PMP22 Antibody (C-Terminus) LS-C50618
IHC Image
Rabbit Polyclonal to Human PMP22
Human
IHC
Unconjugated
PMP22 Mouse IgG1,k Polyclonal Unconjugated Human, Primate IHC Extracellular Domain Yes Primary
Anti-PMP22 Antibody (Extracellular Domain) LS-C33995
PublicationsPublications (1)
IHC Image
Mouse Polyclonal (IgG1,k) to Human PMP22
Human, Primate
IHC
Unconjugated
PMP22 Mouse IgG1,k Monoclonal Hu1 HRP Conjugated Human, Primate IHC-P Extracellular Domain No Primary
Anti-PMP22 Antibody (Extracellular Domain, clone Hu1, HRP) LS-C141617
Mouse Monoclonal [clone Hu1] (IgG1,k) to Human PMP22
Human, Primate
IHC - Paraffin
HRP Conjugated
PMP22 Mouse IgG1,k Monoclonal Hu1 DY550 Conjugated Human, Primate IHC-P Extracellular Domain No Primary
Anti-PMP22 Antibody (Extracellular Domain, clone Hu1, DY550) LS-C141618
Mouse Monoclonal [clone Hu1] (IgG1,k) to Human PMP22
Human, Primate
IHC - Paraffin
DY550 Conjugated
PMP22 Mouse IgG1,k Monoclonal Hu1 DY488 Conjugated Human, Primate IHC-P Extracellular Domain No Primary
Anti-PMP22 Antibody (Extracellular Domain, clone Hu1, DY488) LS-C141616
Mouse Monoclonal [clone Hu1] (IgG1,k) to Human PMP22
Human, Primate
IHC - Paraffin
DY488 Conjugated
PMP22 Mouse IgG1,k Monoclonal Hu1 Biotin Conjugated Human, Primate IHC-P Extracellular Domain No Primary
Anti-PMP22 Antibody (Extracellular Domain, clone Hu1, Biotin) LS-C141614
Mouse Monoclonal [clone Hu1] (IgG1,k) to Human PMP22
Human, Primate
IHC - Paraffin
Biotin Conjugated
PMP22 Mouse IgG1,k Monoclonal Hu1 DY650 Conjugated Human, Primate IHC-P Extracellular Domain No Primary
Anti-PMP22 Antibody (Extracellular Domain, clone Hu1, DY650) LS-C141615
Mouse Monoclonal [clone Hu1] (IgG1,k) to Human PMP22
Human, Primate
IHC - Paraffin
DY650 Conjugated
PMP22 Mouse IgG1 Monoclonal CF1 Unconjugated Human, Orangutan, Gibbon, Monkey IHC-P, WB, ELISA aa121-133 No Primary
Anti-PMP22 Antibody (aa121-133, clone CF1) LS-C122324
Mouse Monoclonal [clone CF1] (IgG1) to Human PMP22
Human, Orangutan, Gibbon, Monkey
IHC - Paraffin, Western blot, ELISA
Unconjugated
PMP22 Rabbit Polyclonal Unconjugated Human IHC C-Terminus No Primary
Anti-PMP22 Antibody (C-Terminus) LS-C189163
Rabbit Polyclonal to Human PMP22
Human
IHC
Unconjugated
PMP22 Mouse IgG1,k Monoclonal Unconjugated Human IHC-P 2nd Extracellular Domain No Primary
Anti-PMP22 Antibody (2nd Extracellular Domain) LS-C74997
Mouse Monoclonal (IgG1,k) to Human PMP22
Human
IHC - Paraffin
Unconjugated
PMP22 Rabbit Polyclonal Unconjugated Mouse, Human WB No Primary
Anti-PMP22 Antibody LS-C164543
WB Image
WB Image
Rabbit Polyclonal to Mouse PMP22
Mouse, Human
Western blot
Unconjugated
PMP22 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa1-160 No Primary
Anti-PMP22 Antibody (aa1-160) LS-C295806
WB Image
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
Unconjugated
PMP22 Rabbit Polyclonal Unconjugated Human, Chimpanzee, Orangutan, Gibbon, Monkey, Bovine, Guinea pig, Rabbit WB aa27-76 No Primary
Anti-PMP22 Antibody (aa27-76) LS-C169727
WB Image
Rabbit Polyclonal to Human PMP22
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Bovine, Guinea pig, Rabbit
Western blot
Unconjugated
PMP22 Rabbit Polyclonal Unconjugated Human WB aa110-140 No Primary
Anti-PMP22 Antibody (aa110-140) LS-C163809
WB Image
Rabbit Polyclonal to Human PMP22
Human
Western blot
Unconjugated
PMP22 Rabbit IgG Monoclonal EPR7088 Unconjugated Human, Rat WB Internal No Primary
Anti-PMP22 Antibody (Internal, clone EPR7088) LS-C152307
WB Image
Rabbit Monoclonal [clone EPR7088] (IgG) to Human PMP22
Human, Rat
Western blot
Unconjugated
PMP22 Rabbit IgG Polyclonal Biotin Conjugated Human WB, ELISA aa1-160 No Primary
Anti-PMP22 Antibody (aa1-160, Biotin) LS-C297936
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
Biotin Conjugated
PMP22 Mouse IgG2b,k Monoclonal 3G10 Unconjugated Human ELISA No Primary
Anti-PMP22 Antibody (clone 3G10) LS-C197931
Mouse Monoclonal [clone 3G10] (IgG2b,k) to Human PMP22
Human
ELISA
Unconjugated
PMP22 Rabbit IgG Polyclonal FITC Conjugated Human WB aa1-160 No Primary
Anti-PMP22 Antibody (aa1-160, FITC) LS-C304846
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot
FITC Conjugated
PMP22 Mouse IgM,k Monoclonal 20-14 Unconjugated Human No Primary
Anti-PMP22 Antibody (clone 20-14) LS-C95378
Mouse Monoclonal [clone 20-14] (IgM,k) to Human PMP22
Human
Unconjugated
PMP22 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human WB, ELISA No Primary
Anti-PMP22 Antibody (Azide-free, HRP) LS-C266604
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
HRP Conjugated, Azide-free
PMP22 Rabbit IgG Polyclonal PE Conjugated Human WB, ELISA No Primary
Anti-PMP22 Antibody (PE) LS-C266628
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
PE Conjugated
PMP22 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa110-140 No
Anti-PMP22 Antibody (aa110-140) LS-C324126
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
Unconjugated
PMP22 Rabbit IgG Polyclonal FITC Conjugated Human WB, ELISA No Primary
Anti-PMP22 Antibody (FITC) LS-C266603
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
FITC Conjugated
PMP22 Rabbit IgG Polyclonal AP Conjugated Human WB, ELISA No Primary
Anti-PMP22 Antibody (AP) LS-C266600
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
AP Conjugated
PMP22 Rabbit IgG Polyclonal APC Conjugated Human WB, ELISA No Primary
Anti-PMP22 Antibody (APC) LS-C266601
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
APC Conjugated
PMP22 Rabbit IgG Polyclonal Biotin Conjugated Human WB, ELISA No Primary
Anti-PMP22 Antibody (Biotin) LS-C266602
Rabbit Polyclonal (IgG) to Human PMP22
Human
Western blot, ELISA
Biotin Conjugated

PMP22 Feature Table


Feature Type Location Details
Disease 1 - 160 Defects in PMP22 are a cause of Dejerine-Sottas syndrome (DSS) [MIM:145900]; also known as Dejerine-Sottas neuropathy (DSN) or hereditary motor and sensory neuropathy III (HMSN3). DSS is a severe degenerating neuropathy of the demyelinating Charcot-Marie- Tooth disease category, with onset by age 2 years. DSS is characterized by motor and sensory neuropathy with very slow nerve conduction velocities, increased cerebrospinal fluid protein concentrations, hypertrophic nerve changes, delayed age of walking as well as areflexia. There are both autosomal dominant and autosomal recessive forms of Dejerine-Sottas syndrome.
Disease 1 - 160 Defects in PMP22 are a cause of hereditary neuropathy with liability to pressure palsies (HNPP) [MIM:162500]; an autosomal dominant disorder characterized by transient episodes of decreased perception or peripheral nerve palsies after slight traction, compression or minor traumas.
Disease 1 - 160 Defects in PMP22 are the cause of Charcot-Marie-Tooth disease type 1A (CMT1A) [MIM:118220]; also known as hereditary motor and sensory neuropathy IA. CMT1A is a form of Charcot-Marie- Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathy or CMT1, and primary peripheral axonal neuropathy or CMT2. Neuropathies of the CMT1 group are characterized by severely reduced nerve conduction velocities (less than 38 m/sec), segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet. CMT1A inheritance is autosomal dominant.
Disease 1 - 160 Defects in PMP22 are the cause of Charcot-Marie-Tooth disease type 1E (CMT1E) [MIM:118300]; also known as Charcot-Marie- Tooth disease and deafness autosomal dominant. CMT1E is an autosomal dominant form of Charcot-Marie-Tooth disease characterized by the association of sensorineural hearing loss with peripheral demyelinating neuropathy.
Disease 1 - 160 Defects in PMP22 may be a cause of inflammatory demyelinating polyneuropathy (IDP) [MIM:139393]. IDP is a putative autoimmune disorder presenting in an acute (AIDP) or chronic form (CIDP). The acute form is also known as Guillain-Barre syndrome.
Function 1 - 160 Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
Similarity 1 - 160 Belongs to the PMP-22/EMP/MP20 family.
Subcellular Location 1 - 160 Membrane; Multi-pass membrane protein.
web resource 1 - 160 Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/PMP22";
web resource 1 - 160 Name=Inherited peripheral neuropathies mutation db; URL="http://www.molgen.ua.ac.be/CMTMutations/";
arrayexpress 1 - 160 Q01453
bgee 1 - 160 Q01453
cleanex 1 - 160 HS_PMP22
ctd 1 - 160 5376
doi 1 - 160 10
eggnog 1 - 160 prNOG20364
embl 1 - 160 BC019040
embl 1 - 160 D11428
embl 1 - 160 L03203
embl 1 - 160 M94048
embl 1 - 160 S61788
embl 1 - 160 X65968
ensembl 1 - 160 ENST00000312280
ensembl 1 - 160 ENST00000395938
ensembl 1 - 160 ENST00000426385
genecards 1 - 160 GC17M015073
geneid 1 - 160 5376
genevestigator 1 - 160 Q01453
germonline 1 - 160 ENSG00000109099
go 1 - 160 GO:0007268
go 1 - 160 GO:0007422
go 1 - 160 GO:0016021
h-invdb 1 - 160 HIX0013554
h-invdb 1 - 160 HIX0039508
hgnc 1 - 160 HGNC:9118
hogenom 1 - 160 HBG443769
hovergen 1 - 160 HBG001690
inparanoid 1 - 160 Q01453
interpro 1 - 160 IPR003936
interpro 1 - 160 IPR004031
interpro 1 - 160 IPR004032
ipi 1 - 160 IPI00007769
kegg 1 - 160 hsa:5376
medline 1 - 160 20095968
medline 1 - 160 21823270
medline 1 - 160 92360032
medline 1 - 160 93246261
medline 1 - 160 93265058
medline 1 - 160 93265095
medline 1 - 160 93265161
medline 1 - 160 93288088
medline 1 - 160 94073197
medline 1 - 160 94100982
medline 1 - 160 94302675
medline 1 - 160 95245343
medline 1 - 160 95282670
medline 1 - 160 95405644
medline 1 - 160 96191764
medline 1 - 160 96209919
medline 1 - 160 96241146
medline 1 - 160 97141911
medline 1 - 160 97151053
medline 1 - 160 97193152
medline 1 - 160 97208855
medline 1 - 160 97331335
medline 1 - 160 98112432
medline 1 - 160 98112478
medline 1 - 160 98204401
medline 1 - 160 98244766
medline 1 - 160 98295578
medline 1 - 160 98418809
medline 1 - 160 99103460
medline 1 - 160 99226460
medline 1 - 160 99264239
medline 1 - 160 99417177
mim 1 - 160 118220
mim 1 - 160 118300
mim 1 - 160 139393
mim 1 - 160 145900
mim 1 - 160 162500
mim 1 - 160 601097
nextbio 1 - 160 20856
oma 1 - 160 YLTGIFQ
orphanet 1 - 160 101081
orphanet 1 - 160 2932
orphanet 1 - 160 640
orphanet 1 - 160 64748
orphanet 1 - 160 65753
orphanet 1 - 160 90658
orphanet 1 - 160 99951
panther 1 - 160 PTHR10671
pathway_interaction_db 1 - 160 a6b1_a6b4_integrin_pathway
pfam 1 - 160 PF00822
pharmgkb 1 - 160 PA33444
phylomedb 1 - 160 Q01453
pir 1 - 160 JN0503
prints 1 - 160 PR01453
prints 1 - 160 PR01458
prosite 1 - 160 PS01221
prosite 1 - 160 PS01222
proteinmodelportal 1 - 160 Q01453
pubmed 1 - 160 10211478
pubmed 1 - 160 10330345
pubmed 1 - 160 10489052
pubmed 1 - 160 10632107
pubmed 1 - 160 10663978
pubmed 1 - 160 10737979
pubmed 1 - 160 11140841
pubmed 1 - 160 11438991
pubmed 1 - 160 11835375
pubmed 1 - 160 12090401
pubmed 1 - 160 12402337
pubmed 1 - 160 12439896
pubmed 1 - 160 12497641
pubmed 1 - 160 12578939
pubmed 1 - 160 12796555
pubmed 1 - 160 1303210
pubmed 1 - 160 1303228
pubmed 1 - 160 1303281
pubmed 1 - 160 1497668
pubmed 1 - 160 15099592
pubmed 1 - 160 15205993
pubmed 1 - 160 15489334
pubmed 1 - 160 16437560
pubmed 1 - 160 7518101
pubmed 1 - 160 7675244
pubmed 1 - 160 7728152
pubmed 1 - 160 7762451
pubmed 1 - 160 8252046
pubmed 1 - 160 8275092
pubmed 1 - 160 8482547
pubmed 1 - 160 8510709
pubmed 1 - 160 8615087
pubmed 1 - 160 8655153
pubmed 1 - 160 8777804
pubmed 1 - 160 8988161
pubmed 1 - 160 8995589
pubmed 1 - 160 9004143
pubmed 1 - 160 9040744
pubmed 1 - 160 9055797
pubmed 1 - 160 9187667
pubmed 1 - 160 9452053
pubmed 1 - 160 9452099
pubmed 1 - 160 9544841
pubmed 1 - 160 9585367
pubmed 1 - 160 9633821
pubmed 1 - 160 9748013
pubmed 1 - 160 9888385
refseq 1 - 160 NP_000295.1
refseq 1 - 160 NP_696996.1
refseq 1 - 160 NP_696997.1
string 1 - 160 Q01453
ucsc 1 - 160 uc002goj.1
unigene 1 - 160 Hs.372031
carbohyd 41 - 41 N-linked (GlcNAc...) (Potential)
chain 1 - 160 Peripheral myelin protein 22 /FTId=PRO_0000164650.
transmem 2 - 31 Helical; (By similarity)
transmem 65 - 91 Helical; (By similarity)
transmem 96 - 119 Helical; (By similarity)
transmem 134 - 156 Helical; (By similarity)
variant 12 - 12 H -> Q (in DSS) /FTId=VAR_006359.
variant 16 - 16 L -> P (in CMT1A and DSS) /FTId=VAR_006360.
variant 19 - 19 L -> P (in DSS) /FTId=VAR_006361.
variant 22 - 22 S -> F (in HNPP and CMT1A) /FTId=VAR_029960.
variant 23 - 23 T -> R (in CMT1E) /FTId=VAR_029961.
variant 25 - 26 Missing (in CMT1A) /FTId=VAR_029962.
variant 28 - 28 W -> R (in CMT1E) /FTId=VAR_029963.
variant 30 - 30 V -> M (in HNPP) /FTId=VAR_009659.
variant 37 - 37 D -> V (in CMT1A; with focally folded myelin sheaths). /FTId=VAR_009660.
variant 65 - 65 V -> F (in CMT1A) /FTId=VAR_029964.
variant 67 - 67 A -> P (in CMT1E) /FTId=VAR_009661.
variant 67 - 67 A -> T (in HNPP) /FTId=VAR_029965.
variant 69 - 69 M -> K (in DSS) /FTId=VAR_006362.
variant 71 - 71 L -> P (in DSS) /FTId=VAR_029966.
variant 72 - 72 S -> L (in DSS and CMT1A) /FTId=VAR_006363.
variant 72 - 72 S -> P (in DSS) /FTId=VAR_006364.
variant 72 - 72 S -> W (in DSS) /FTId=VAR_006365.
variant 76 - 76 S -> I (in DSS) /FTId=VAR_006366.
variant 79 - 79 S -> C (in CMT1A) /FTId=VAR_006367.
variant 79 - 79 S -> P (in DSS) /FTId=VAR_006368.
variant 80 - 80 L -> P (in DSS) /FTId=VAR_006369.
variant 80 - 80 L -> R (in DSS) /FTId=VAR_029967.
variant 84 - 84 Missing (in DSS) /FTId=VAR_006370.
variant 93 - 93 G -> R (in CMT1A) /FTId=VAR_009662.
variant 100 - 100 G -> E (in DSS) /FTId=VAR_006371.
variant 100 - 100 G -> R (in DSS) /FTId=VAR_006372.
variant 105 - 105 L -> R (in CMT1A and DSS) /FTId=VAR_006373.
variant 107 - 107 G -> V (in CMT1A) /FTId=VAR_006374.
variant 109 - 109 C -> R (in DSS) /FTId=VAR_029968.
variant 115 - 118 Missing (in CMT1E) /FTId=VAR_029969.
variant 118 - 118 T -> M (in CMT1A) /FTId=VAR_006375.
variant 137 - 137 I -> V /FTId=VAR_006376.
variant 147 - 147 L -> R (in CMT1A) /FTId=VAR_006377.
variant 149 - 149 S -> R (in DSS) /FTId=VAR_029970.
variant 150 - 150 G -> C (in DSS) /FTId=VAR_006378.
variant 150 - 150 G -> D (in DSS) /FTId=VAR_006379.
variant 157 - 157 R -> G (in dbSNP:rs28936682) /FTId=VAR_009663.
variant 157 - 157 R -> W (in DSS; dbSNP:rs28936682) /FTId=VAR_009664.
keyword 1 - 160 Charcot-Marie-Tooth disease
keyword 1 - 160 Complete proteome
keyword 1 - 160 Deafness
keyword 1 - 160 Dejerine-Sottas syndrome
keyword 1 - 160 Disease mutation
keyword 1 - 160 Glycoprotein
keyword 1 - 160 Membrane
keyword 1 - 160 Neuropathy
keyword 1 - 160 Polymorphism
keyword 1 - 160 Transmembrane
keyword 1 - 160 Transmembrane helix
Molecular Weight 1 - 160 17891
1 hit 1 - 160 PF00822
1 hit 1 - 160 PS01221
1 hit 1 - 160 PS01222

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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