PIK3C2B

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta

PIK3C2B belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

PIK3C2B (5)

Publications

No (5)

Tag

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Rat (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human PIK3C2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82009

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

184.6 kDa

Price:

20 µg/$215

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Human PIK3C2B Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G59603

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PIK3C2B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68364

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

184.6 kDa

Price:

20 µg/$1,107

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Rat PIK3C2B Protein (Recombinant His-T7) (aa790-1025) - LS-G16043

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.5 kDa

Price:

10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029

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PIK3C2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117840

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

184.6 kDa

Price:

100 µg/$710

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