Osteonectin / SPARC

secreted protein, acidic, cysteine-rich (osteonectin)

SPARC (secreted protein acidic and rich in cysteine)/Osteonectin is a matricellular glycoprotein that modulates cellular interactions with the ECM and is expressed in tissues undergoing remodeling. It functions as a de-adhesive protein, as a modulator of growth factor activity, and as a cell-cycle inhibitor. It induces changes in endothelial cell shape via F-actin, coincident with the appearance of intercellular gaps, that provide a paracellular pathway for extravasation of macromolecules. Tumor growth is enhanced in mice lacking SPARC due to changes in the ECM that create a more permissive environment for tumor progression.

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Products

ELISA Kits (32)

Type

Competitive EIA (1)

Custom (5)

Development Kit (3)

Sandwich (21)

Sandwich CLIA (2)

Target

Osteonectin / SPARC (32)

Reactivity

Human (10)

Mouse (8)

Rat (6)

Chicken (2)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Product Group

DevKit DuoPlus (3)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (4)

96-Well Strip Plate (23)

Antibody Pair and Standard (3)

Publications

No (31)

Yes (1)

Sample Type

Cell Culture Supernatants (7)

Cell Lysates (4)

Milk (1)

Plasma (20)

Serum (22)

Tissue Homogenates (11)

Urine (1)

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Mouse Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F21843

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rat Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F23595

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F4333

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Human Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F22075

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F4332

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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Mouse Osteonectin / SPARC (CLIA) ELISA Kit - LS-F30886

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

0.625 - 40 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Chicken Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F46419

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F46422

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F46423

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F46424

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F46425

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Human Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F52660

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$897

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Mouse Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F53302

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$822

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DevKit DuoPlus Mouse Osteonectin / SPARC ELISA Development Kit - LS-F71723

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,207; 1000 Wells/$1,787

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DevKit DuoPlus Rat Osteonectin / SPARC ELISA Development Kit - LS-F71865

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Rat

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,254; 1000 Wells/$1,867

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DevKit DuoPlus Human Osteonectin / SPARC ELISA Development Kit - LS-F71628

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

6.24 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,182; 1000 Wells/$1,747

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Human Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F2890

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Milk, Serum

Price:

1 Plate/$699

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Human Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F24666

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

780 - 50000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Serum

Price:

1 Plate/$624

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Rat Osteonectin / SPARC (Custom ELISA) ELISA Kit - LS-F15221

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Chicken Osteonectin / SPARC (Custom ELISA) ELISA Kit - LS-F15216

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse Osteonectin / SPARC (Custom ELISA) ELISA Kit - LS-F15217

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Pig Osteonectin / SPARC (Custom ELISA) ELISA Kit - LS-F15218

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Bovine Osteonectin / SPARC (Custom ELISA) ELISA Kit - LS-F15219

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F4331

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$695

Select

Human Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F27101

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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