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Neuropeptide Y / NPY

neuropeptide Y

Neuropeptide Y / NPY is a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.

Gene Name: neuropeptide Y
Family/Subfamily: Pancreatic hormone , not assigned-Pancreatic hormone
Synonyms: NPY, Pro-neuropeptide Y, Neuropeptide Y, PYY4
Target Sequences: NM_000905 NP_000896.1 P01303

Publications (1)

1
Central anorexigenic actions of bile acids are mediated by TGR5. Alessia Perino, Laura A Velázquez-Villegas, Nadia Bresciani, Yu Sun, Qingyao Huang, Valérie S Fénelon, Ashley Castellanos-Jankiewicz, Philippe Zizzari, Giuseppe Bruschetta, Sungho Jin, Aiste Baleisyte, Antimo Gioiello, Roberto Pellicciari, Julijana Ivanisevic, Bernard L Schneider, Sabrina Diano, Daniela Cota, Kristina Schoonjans. Nature metabolism. 2021 May;3:595-603. [Full Text Article] [PubMed:34031591] [PMC:PMC7610881]

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ELISA Kits (23)
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Neuropeptide Y / NPY (23)
Human (6)
Mouse (5)
Rat (4)
Bovine (3)
Chicken (1)
Guinea pig (2)
Pig (2)
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Rabbit (1)
96-Well Microplate (2)
96-Well Strip Plate (21)
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Yes (1)
Cell Culture Supernatants (8)
Cell Lysates (7)
Plasma (18)
Serum (19)
Tissue Homogenates (11)
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
2.47 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
2.47 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Microplate
Mouse, Human, Rat
0.1 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$505
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Bovine
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$779
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Porcine
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$565
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$565
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Guinea pig
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$565
Neuropeptide Y / NPY ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
Neuropeptide Y / NPY ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Bovine
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Neuropeptide Y / NPY ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$822
Neuropeptide Y / NPY ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
2.47 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$748
Neuropeptide Y / NPY ELISA Kit
Select
Competitive EIA
96-Well Microplate
Guinea pig
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$612
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).